“…Tests of prothrombin time (PT) and activated partial thromboplastin time (APTT) are major screening methods to evaluate the endogenous coagulation pathway and the anomaly in the coagulation factor II, V and X or fibrinogen (Devreese, 2021). Plasma fibrinogen, also known as the coagulation factor I, is a protein that is mainly distributed in plasma that is involved in the process of blood coagulation, and is a soluble precursor of fibrin that could be transformed into the fibrin at the last stage of coagulation (May et al, 2021;Syyam et al, 2022). Any increase in the level of fibrinogen could further elevate the risk of thromboembolism, which is frequently seen in the patients with diabetes mellitus or acute myocardial infarction.…”