“…13,15,[21][22][23] The data from a recent study indicated that an atherogenic diet reformulated with sesame oil showed antiatherosclerotic and antiinflammatory actions by reducing the atherosclerotic lesions, plasma cholesterol, TG and LDL-C levels, and plasma inflammatory cytokines in lipoprotein receptor knock-out mice. 30 Helli et al 31 demonstrated that consumption of sesamin reduced the body weight, blood pressure, and lipid profile in women suffering with rheumatoid arthritis. Other studies have also reported that dietary sesamin reduced the plasma TC accompanied by increased excretion of total fecal neutral and acidic steroids and downregulated mRNA of intestinal NPC1L1, ACAT-2, MTP, ABCG5, and ABCG8, all of which are considered vital factors for cholesterol absorption in the intestine.…”