Anti‐cancer Herbal Drug Berberine – Sensitive Determination Using Boron‐doped Diamond Electrode

Stanković, Dalibor M.; Samphao, Anchalee; Kalcher, Kurt

doi:10.1002/elan.201500356

Cited by 10 publications

(4 citation statements)

References 28 publications

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“…This current increase is proportional to the increase of the square root of the scan rate (Figure B) which can be expressed with the corresponding equation: I p (μA)=0.1192+0.5531 v 1/2 (mV/s) 1/2 with R 2 =0.9960. Thus, the nature of the electrochemical reaction for the oxidation of COLC at BDDE surface can be assigned to the diffusion controlled processes . This fact confirms the advantages of the BDDE and approves its usage as modification‐free electrochemical sensor.…”

Section: Resultssupporting

confidence: 68%

“…In the last decade, BDDE is widely investigated by the several groups of the researchers, including our working group, due to its characteristics such as negligible adsorption, low background current, wide usable potential range as well as excellent selectivity and sensitivity. This electrode is often used for detection of miscellaneous biological active compounds, toxic organic pollutants and important biological molecules in various kinds of samples .…”

Section: Introductionmentioning

confidence: 99%

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Electrochemical Determination of Natural Drug Colchicine in Pharmaceuticals and Human Serum Sample and its Interaction with DNA

et al. 2017

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Colchicine (COLC) is a natural toxic product and secondary metabolite most commonly used to treat gout. In this study, its electrochemical behavior and determination was investigated by employing modification‐free boron‐doped diamond electrode (BDDE). Besides, its interaction with DNA was monitored using electrochemical methods. It was found that oxidation of this compound proceeds in two steps, where first sharp and well defined oxidation peak occurs at potential of around 1.19 V, and second one at around 1.37 V, in Britton‐Robinson buffer solution at pH 7.5. Wide dynamic range from 1 to 100 μM was obtained with a detection limit (3σintercept/slope) of a 0.26 μM, based on the evaluation of first oxidation peak using differential pulse voltammetry. The proposed method was also found to be suitable for monitoring interaction of this drug with DNA as important segment for medical use. Concerning the validation, the analytical procedure shows excellent selectivity and sensitivity toward COLC detection and after method development it was successfully used for its quantification in pharmaceutical preparation and human serum sample, with satisfactory recovery. Obviously, this approach can be promising replacement for time‐consuming and expensive separation methods.

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Section: Resultssupporting

confidence: 68%

Section: Introductionmentioning

confidence: 99%

Electrochemical Determination of Natural Drug Colchicine in Pharmaceuticals and Human Serum Sample and its Interaction with DNA

et al. 2017

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“…Characteristics of BDD electrodes are low background current, negligible adsorption and wide working potential. Due to that, this electrode, nowadays, plays important role in electroanalytical chemistry and is applied in different fields, from environmental analysis to the analysis of biological active compounds .…”

Section: Introductionmentioning

confidence: 99%

Electroanalytical Approach for Quantification of Pesticide Maneb

Stanković

2016

Electroanalysis

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For the first time, in this study electrochemical oxidation behavior of pesticide maneb is evaluated. Due to the structure electroanalytical quantification of maneb has not been exploited enough. Maneb electrochemical behavior was investigated using glassy carbon (GC), graphene modified glassy carbon (GR/GC) and boron doped diamond (BDD) electrodes. It is shown that only BDD shows satisfactory results toward maneb detection. Based on this, a simple, sensitive and selective electroanalytical method for determination of pesticide maneb using differential pulse voltammetry (DPV) is proposed, with a working linear range of 80–3000 nM and the limit of detection of 24 nM. The developed methodology has been applied for the determination of maneb in river water samples with satisfactory recovery. Additionally, this green method, being simple, fast, and free of chemical‐reduction reagents, offers several advantages over modified electrodes and expands the scope of BDD based electrochemical sensing devices, with promise for wider applications in environmental analysis.

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“…[21][22][23] Several research groups, including ours, study the electrochemical behavior and application of electrode materials in electroanalytical methods to quantify natural compounds. [24][25][26][27][28][29][30][31][32][33] To the best of our knowledge, there is only one published peer-reviewed study about determination of TUB using electrochemical procedure based on ion selective membrane method. 34 Based on the importance of this biological compound for various applications, gaining more insight in electrochemical behavior should be essential for scientist working in the field of electrochemistry.…”

mentioning

confidence: 99%

Electrochemistry of the Arrow Poison, Tubocurarine, Using Boron Doped Diamond Electrode: Experimental and Theoretical Approaches

Đurđić

Stanković

Perić

et al. 2019

J. Electrochem. Soc.

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In present work boron doped diamond (BDD) electrode was applied for studying electrochemical behavior, as well as for quantitative determination of natural alkaloid, tubocurarine (arrow poison/ TUB). Electrochemical behavior was investigated using several organic solvents and aqueous buffers, at different pHs, as supporting electrolytes. After selection of the most appropriate supporting electrolyte and investigation of its electrochemical behavior, analytical procedures for quantitative analysis of TUB were developed in an acetonitrile/methanol (80:20) mixture and in 1 mol L −1 nitric acid, which had linear quantification ranges from 4 × 10 −6 to 1 × 10 −4 mol L −1 (LOD = 3.07 × 10 −6 mol L −1 ) and 4 × 10 −6 to 9 × 10 −5 mol L −1 (LOD = 2.45 × 10 −6 mol L −1 and 5.28 × 10 −7 mol L −1 , depending on the selected peak), respectively. The oxidation mechanism of TUB was proposed from the theoretical aspect. Remarkable selectivity and good sensitivity were obtained after the TUB quantification method was optimized, allowing application of the developed method for TUB quantification in biological fluids, with excellent reproducibility, accuracy and precision.

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Anti‐cancer Herbal Drug Berberine – Sensitive Determination Using Boron‐doped Diamond Electrode

Cited by 10 publications

References 28 publications

Electrochemical Determination of Natural Drug Colchicine in Pharmaceuticals and Human Serum Sample and its Interaction with DNA

Electrochemical Determination of Natural Drug Colchicine in Pharmaceuticals and Human Serum Sample and its Interaction with DNA

Electroanalytical Approach for Quantification of Pesticide Maneb

Electrochemistry of the Arrow Poison, Tubocurarine, Using Boron Doped Diamond Electrode: Experimental and Theoretical Approaches

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