Anti-cancer properties and catalytic oxidation of sulfides based on vanadium(V) complexes of unprotected sugar-based Schiff-base ligands

Mokhtari, Parisa; Mohammadnezhad, Gholamhossein

doi:10.1016/j.poly.2022.115655

Cited by 12 publications

(4 citation statements)

References 81 publications

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“…It is interesting to note that the free ligand was inactive against bacteria. Particularly, Lc (33) was the most active against C. albicans. [Gd2(C26H28O2N6)2( NO3)6]•6H2O [82] reported the synthesis and antibacterial and antioxidant activity of some SBs with transition metals and actinides.…”

Section: Sbs Complexes With Transition Metalsmentioning

confidence: 99%

“…The highly stable complexes formed by SBs with transition metals often lead to compounds with strongly enhanced activities in inorganic [22,23] and bioinorganic chemistry [24], materials science [25], and pharmacology for biomedical applications [26][27][28][29][30]. The most described biological activities regarding the SBs complexes are antitumoral [31][32][33][34][35], antioxidant [36,37], antidiabetic [38][39][40][41], antimalarial [42], antiarthritic [43], antimicrobial [44][45][46][47][48], neuroprotective, catalase-like and catecholase-like enzymatic [49,50], and DNA-binding [51,52]. Recently, Aggarwal et al (2022) [53] underlined the potential applicability of some SBs and their metal complexes for the treatment of COVID-19 [54], which may represent valid alternatives to the classic treatments for this disease [55,56].…”

Section: Introductionmentioning

confidence: 99%

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Metal Complexes with Schiff Bases as Antimicrobials and Catalysts

Iacopetta,

Ceramella,

Catalano

et al. 2023

Inorganics

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Complexes of Schiff bases (SBs) with metals are promising compounds exhibiting a broad range of applications, such as catalysts, polymers, dyes, and several biological activities, including antimicrobial, anticancer, antioxidant, antimalarial, analgesic, antiviral, antipyretic, and antidiabetic actions. Considering the crisis that the whole world is now facing against antimicrobial-resistant bacteria, in the present review, we chose to focus on the activity of SBs as antimicrobials, particularly underlying the most recent studies in this field. Finally, some interesting catalytic applications recently described for metal complexes with SBs have also been discussed.

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Section: Sbs Complexes With Transition Metalsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Metal Complexes with Schiff Bases as Antimicrobials and Catalysts

Iacopetta,

Ceramella,

Catalano

et al. 2023

Inorganics

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“…A variety of 2,3-bifunctionalized quinoxalines (56)(57)(58)(59)(60)(61) have been prepared by the condensation of 1,6-disubstituted-hexan-1,3,4,6-tetraones with o-phenylenediamine, (R,R)-1,2-diaminocyclohexane, and p-nitro-o-phenylenediamine [86][87][88]. The antifungal activity of six prepared quinoxaline compounds' antifungal activity was measured against F.o.a, as described in the method in the literature [48].…”

Section: Quinoxalinesmentioning

confidence: 99%

“…N,N -bipyrazole piperazine derivatives [50] are established as polypharmacological mixed ligands with several biological activities reported in the literature [51][52][53][54]. Meanwhile, Schiff base derivatives [53] have different biological functions, such as anti-inflammatory [55], antifungal [56], and antibacterial effects [57], and are commonly used as carriers of catalysts [58], optical chemical receptors [59], thermo-stable products [60], agents of metal complexion [61], inhibitors of corrosion [62], and stabilizers of polymers [63].…”

Section: Introductionmentioning

confidence: 99%

An Insight into All Tested Small Molecules against Fusarium oxysporum f. sp. Albedinis: A Comparative Review

et al. 2022

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Bayoud disease affects date palms in North Africa and the Middle East, and many researchers have used various methods to fight it. One of those methods is the chemical use of synthetic compounds, which raises questions centred around the compounds and common features used to prepare targeted molecules. In this review, 100 compounds of tested small molecules, collected from 2002 to 2022 in Web of Sciences, were divided into ten different classes against the main cause of Bayoud disease pathogen Fusarium oxysporum f. sp. albedinis (F.o.a.) with structure–activity relationship (SAR) interpretations for pharmacophore site predictions as (δ−···δ−), where 12 compounds are the most efficient (one compound from each group). The compounds, i.e., (Z)-1-(1.5-Dimethyl-1H-pyrazole-3-yl)-3-hydroxy but-2-en-1-one 7, (Z)-3-(phenyl)-1-(1,5-dimethyl-1H-pyrazole-3-yl)-3-hydroxyprop-2-en-1-one 23, (Z)-1-(1,5-Dimethyl-1H-pyrazole-3-yl)-3-hydroxy-3-(pyridine-2-yl)prop-2-en-1-one 29, and 2,3-bis-[(2-hydroxy-2-phenyl)ethenyl]-6-nitro-quinoxaline 61, have antifungal pharmacophore sites (δ−···δ−) in common in N1---O4, whereas other compounds have only one δ− pharmacophore site pushed by the donor effect of the substituents on the phenyl rings. This specificity interferes in the biological activity against F.o.a. Further understanding of mechanistic drug–target interactions on this subject is currently underway.

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