Anti-coccidial activity of the ethanol extract of Tribulus terrestris fruits on Eimeria tenella

Abstract

Anti-coccidial effects of the fruits of Tribulus terrestris (Tribuli fructus) ethanol extract (TTE) were studied with animal experiment following per oral administration with Eimeria (E.) tenella. This experiment was performed on the 3-day-old chicks (n=30). The animals were divided with 3 groups; TFE 15mg per animal+infected (n=10), TTE untreated+infected (n=10) and non-infected control (n=10). Animals were administrated with or without TTE during 1 week, and then inoculated with E. tenella. The anti-coccidial activity were evaluated with oocysts shedding numbers in stools, body weights changes and food intake changes. The TTE-inoclated animals revealed significantly decreased stool oocysts numbers (P<0.05) when compared to the TTE untreated animals. Also, TTE-treated animals showed more increased body weight gains (P<0.05) than the TTE untreated animals. These results demonstrate that TTE produce anticoccidial activities against E. tenella. TTE could be a promising treatment for the coccidiosis.

Chemicolome and Metabolome Profiling of Xieriga-4 Decoction, A Traditional Mongolian Medicine, Using the UPLC-QTOF/MS Approach

“…TF has anti-infective and diuretic activities and has been used to treat hypertension and edema. TF contains steroidal saponins, alkaloids, and flavonoids [ 10 ]. The fragments of hecogenin 3-O- β -glucopyranosyl (1⟶2)- β - glucopyranosyl (1⟶4) galactopyranoside were produced at m/ z 755, m/ z 593, m/z 431 by glycosyl losses, and m/ z 317 by steroidal ring cracking, respectively.…”

“…TF has anti-infective and diuretic activities and has been used to treat hypertension and edema. TF contains steroidal saponins, alkaloids, and favonoids [10]. Te fragments of hecogenin galactopyranoside (P55), and oxy-berberine (P58) (for details, see Table S2).…”