Anti-edematogenic and analgesic activities of Ficus benghalensis

Abstract

This work was done for the investigations of anti-inflammatory and analgesic activities of methanolic extract of dried leaves of Ficus benghalensis Linn. by oral administration at doses of 10, 20 and 100 mg/kg of body weight to healthy animals. The extract was studied for anti-inflammatory activity by using carrageenan-induced hind paw edema in rats. The mean increases in paw volume and % inhibition in the edema were measured plethysmometrically at different time intervals after carrageenan (1% w/v) injection. The extract was also evaluated for analgesic activity using acetic acid-induced writhing and Eddy's hot plate method in albino mice. The methanolic extract of F. benghalensis showed significant (P<0.05) reduction in carrageenan-induced paw edema and analgesic activity evidenced from decreased acetic acid-induced writhings and increased reaction time in Eddy's hot plate method. Results of present studies suggest that methanolic extract of F. benghalensis possesses significant (P<0.05) anti-inflammatory and analgesic activities.

Effect of root-extracts of Ficus benghalensis (Banyan) in pain in animal models

“…Most past studies have, however, shown that different plant-parts, namely bark[ 9 ] and leaves[ 3 9 ] did have analgesic and anti-inflammatory properties.…”

“…In allopathy, pharmacological screening of plants often provides basis for developing new lead molecules. [ 2 3 ]…”

“…verified significant analgesic activities of methanolic extract of leaves of F. benghalensis . [ 3 ]…”

Effect of root-extracts of Ficus benghalensis (Banyan) in memory, anxiety, muscle co-ordination and seizure in animal models

“…Even in allopathy, pharmacological screening of plants often provide basis for developing new lead molecules [1, 2]. The recent advancements in phyto-chemistry and molecular biology have renewed and rejuvenated our interest in herbal medicines.…”

“…There have been many attempts to prove analgesic and anti-inflammatory [2, 13], antistress and antiallergic [14], antimicrobial [15, 16], antiplasmodial [17], mosquito larvicidal [18] anti-ulcer [19], antifungal [20], anti-lipidemic [21] anti-atherogenic [22] antidiabetic [23, 24] properties of various parts of the plant. Though mainstream medicine has claimed several interesting findings, no break-through has yet been achieved [25].…”