Anti-HIV-1 Activities of Aerial Parts of Ocimum basilicum and its Parasite Cuscuta campestris

Behbahani, ana; Mohabatkar, Hassan; Soltani, Mohammad

doi:10.4172/jaa.1000064

Cited by 20 publications

(11 citation statements)

References 27 publications

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“…Molecules 2021, 26, 6387 2 of 25 EOs are obtained from different plant organs. The most widely used are flowers (Jasminum spp., Rosa spp., Viola spp., Lavandula spp., S. aromaticum L.), leaves (Thymus vulgaris, Eucalyptus spp., Lippia graveolens, Ocimum basilicum, Salvia rosmarinus, Cymbopogon citratus, Melaleuca alternifolia), fruits (Illicium verum, Citrus sinensis, Citrus limon), seeds (M, Coffea arabica, Piper nigrum L.), bark (Cinnamomum spp.…”

Section: Introductionmentioning

confidence: 99%

Clove Essential Oil (Syzygium aromaticum L. Myrtaceae): Extraction, Chemical Composition, Food Applications, and Essential Bioactivity for Human Health

et al. 2021

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Clove (Syzygium aromaticum L. Myrtaceae) is an aromatic plant widely cultivated in tropical and subtropical countries, rich in volatile compounds and antioxidants such as eugenol, β-caryophyllene, and α-humulene. Clove essential oil has received considerable interest due to its wide application in the perfume, cosmetic, health, medical, flavoring, and food industries. Clove essential oil has biological activity relevant to human health, including antimicrobial, antioxidant, and insecticidal activity. The impacts of the extraction method (hydrodistillation, steam distillation, ultrasound-assisted extraction, microwave-assisted extraction, cold pressing, and supercritical fluid extraction) on the concentration of the main volatile compounds in clove essential oil and organic clove extracts are shown. Eugenol is the major compound, accounting for at least 50%. The remaining 10–40% consists of eugenyl acetate, β-caryophyllene, and α-humulene. The main biological activities reported are summarized. Furthermore, the main applications in clove essential oil in the food industry are presented. This review presents new biological applications beneficial for human health, such as anti-inflammatory, analgesic, anesthetic, antinociceptive, and anticancer activity. This review aims to describe the effects of different methods of extracting clove essential oil on its chemical composition and food applications and the biological activities of interest to human health.

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Section: Introductionmentioning

confidence: 99%

Clove Essential Oil (Syzygium aromaticum L. Myrtaceae): Extraction, Chemical Composition, Food Applications, and Essential Bioactivity for Human Health

et al. 2021

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“…It produces a number of antiviral bioactive compounds, such as ursolic acid, eugenol, 1,8-cineole, and rosmarinic acid which exhibit potential to inhibit HSV-I and II ( Caamal-Herrera et al, 2016 ). O. basilicum , known as sweet basil, contains 1,8-cineole, camphor, thymol, eugenol, eugenol epoxide, apigenin, linalool, and ursolic acid which have been reported to work against HIV-I, HSV, ADV-3, 8, 11, HVB, EV, and CVB-I ( Behbahani et al, 2013 ; Kubiça et al, 2014 ; Tshilanda et al, 2020 ). O. gratissimum is an aromatic herb which is commonly known as African basil.…”

Section: Antiviral Plants Of Bangladeshmentioning

confidence: 99%

A Review of Medicinal Plants with Antiviral Activity Available in Bangladesh and Mechanistic Insight Into Their Bioactive Metabolites on SARS-CoV-2, HIV and HBV

et al. 2021

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Currently, viral infection is the most serious health issue which causing unexpected higher rate of death globally. Many viruses are not yet curable, such as corona virus-2 (SARS-CoV-2), human immunodeficiency virus (HIV), hepatitis virus, human papilloma virus and so others. Furthermore, the toxicities and ineffective responses to resistant strains of synthetic antiviral drugs have reinforced the search of effective and alternative treatment options, such as plant-derived antiviral drug molecules. Therefore, in the present review, an attempt has been taken to summarize the medicinal plants reported for exhibiting antiviral activities available in Bangladesh along with discussing the mechanistic insights into their bioactive components against three most hazardous viruses, namely SARS-CoV-2, HIV, and HBV. The review covers 46 medicinal plants with antiviral activity from 25 families. Among the reported 79 bioactive compounds having antiviral activities isolated from these plants, about 37 of them have been reported for significant activities against varieties of viruses. Hesperidin, apigenin, luteolin, seselin, 6-gingerol, humulene epoxide, quercetin, kaempferol, curcumin, and epigallocatechin-3-gallate (EGCG) have been reported to inhibit multiple molecular targets of SARS-CoV-2 viral replication in a number of in silico investigations. Besides, numerous in silico, in vitro, and in vivo bioassays have been demonstrated that EGCG, anolignan-A, and B, ajoene, curcumin, and oleanolic acid exhibit anti-HIV activity while piperine, ursolic acid, oleanolic acid, (+)-cycloolivil-4′-O-β-d-glucopyranoside, quercetin, EGCG, kaempferol, aloin, apigenin, rosmarinic acid, andrographolide, and hesperidin possess anti-HBV activity. Thus, the antiviral medicinal plants and the isolated bioactive compounds may be considered for further advanced investigations with the aim of the development of effective and affordable antiviral drugs.

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“…Eugenol is a volatile compound that varies from colorless to light yellow, has low water solubility (approximately 2460 mg/L at 25 °C), a strong odor, and an intense flavor. Among the reported biological activities of eugenol is insecticide activity, antimicrobial, anti-inflammatory, wound healing, antiviral, antioxidant, and anticancer [7,8,[14][15][16][17][18].…”

Section: Clove Essential Oil (Ceo)mentioning

confidence: 99%

“…Eugenol has also been studied as a possible inhibitor of the initial stage of infection by the HIV-1 virus because it can reduce virus replication. Likewise, eugenol can increase lymphocyte production; therefore, the lymphocyte proliferation capacity of eugenol may be responsible for anti-HIV-1 activity [16].…”

Section: Antiviralmentioning

confidence: 99%

Clove Essential Oil (<em>Syzygium aromaticum L. Myrtaceae</em>): Extraction, Chemical Composition, Food Applications and Essential Bioactivities for Human Health

Haro-González¹,

Castillo-Herrera²,

Martínez-Velázquez³

et al. 2021

Preprint

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Clove (Syzygium aromaticum L. Myrtaceae) is an aromatic plant widely cultivated in tropical and subtropical countries, rich in volatile compounds and antioxidants such as eugenol, β-caryophyllene, and α-humulene. Clove essential oil has received considerable interest due to its wide application in the perfumery, cosmetic, health, medical, flavoring, and food industries. Clove essential oil has relevant biological activities to human health, including antimicrobial, antioxidant, and insecticide. This review describes the effect of the extraction method (hydrodistillation, steam distillation, ultrasound-assisted extraction, microwave-assisted extraction, cold pressing, and supercritical fluid extraction) on the chemical composition of essential oil and its correlation with their biological activities. Likewise, are summarized the main compounds and their reported biological activities. Furthermore, the main applications in clove essential oil in the food industry are presented. Finally, this review presents the new biological activities such as anti-inflammatory, analgesic, anesthetic, antinociceptive and anticancer, which are beneficial for human health. This review aims to compile the effect of different methods of extracting clove essential oil on chemical composition, food applications, as well as a current description of biological activities of interest to human health. Biological activities have increased interest in research into this essential oil and its future applications in the food or pharmaceutical industry.

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Anti-HIV-1 Activities of Aerial Parts of Ocimum basilicum and its Parasite Cuscuta campestris

Cited by 20 publications

References 27 publications

Clove Essential Oil (Syzygium aromaticum L. Myrtaceae): Extraction, Chemical Composition, Food Applications, and Essential Bioactivity for Human Health

Clove Essential Oil (Syzygium aromaticum L. Myrtaceae): Extraction, Chemical Composition, Food Applications, and Essential Bioactivity for Human Health

A Review of Medicinal Plants with Antiviral Activity Available in Bangladesh and Mechanistic Insight Into Their Bioactive Metabolites on SARS-CoV-2, HIV and HBV

Clove Essential Oil (<em>Syzygium aromaticum L. Myrtaceae</em>): Extraction, Chemical Composition, Food Applications and Essential Bioactivities for Human Health

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