Anti-inflammatory abietanes diterpenes and triterpenoids isolated from Clinopodium polycephalum

Liu, Yaxuan; Song, Huijie; Xu, Jixuan; Bi, Guangming; Meng, Dali

doi:10.1016/j.fitote.2022.105244

Cited by 9 publications

(1 citation statement)

References 12 publications

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“…Wu and S.J. Hsuan Saturol I; 3β-22, 25-dihydroxy-tirucalla-7, 23-dieno; maslinic acid; 2α, 3α-dihydroxyolean-12-en-28-oic acid; hederagenin; 2α, 3α-dihydroxyursolic acid; alphitolic acid; rosmarinic acid; and hesperidin [136] Table 1. Cont.…”

Section: Species Secondary Metabolites With Anti-inflammatory Activit...mentioning

confidence: 99%

Ethnobotanical, Phytochemical, and Pharmacological Properties of the Subfamily Nepetoideae (Lamiaceae) in Inflammatory Diseases

Ortiz-Mendoza,

Martínez-Gordillo,

Martínez-Ambriz

et al. 2023

Plants

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Nepetoideae is the most diverse subfamily of Lamiaceae, and some species are well known for their culinary and medicinal uses. In recent years, there has been growing interest in the therapeutic properties of the species of this group regarding inflammatory illnesses. This study aims to collect information on traditional uses through ethnobotanical, pharmacological, and phytochemical information of the subfamily Nepetoideae related to inflammatory diseases. UNAM electronic resources were used to obtain the information. The analysis of the most relevant literature was compiled and organised in tables. From this, about 106 species of the subfamily are traditionally recognised to alleviate chronic pain associated with inflammation. Pharmacological studies have been carried out in vitro and in vivo on approximately 308 species belonging to the genera Salvia, Ocimum, Thymus, Mentha, Origanum, Lavandula, and Melissa. Phytochemical and pharmacological evaluations have been performed and mostly prepared as essential oil or high polarity extracts, whose secondary metabolites are mainly of a phenolic nature. Other interesting and explored metabolites are diterpenes from the abietane, clerodane, and kaurane type; however, they have only been described in some species of the genera Salvia and Isodon. This review reveals that the Nepetoideae subfamily is an important source for therapeutics of the inflammatory process.

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Section: Species Secondary Metabolites With Anti-inflammatory Activit...mentioning

confidence: 99%

Ethnobotanical, Phytochemical, and Pharmacological Properties of the Subfamily Nepetoideae (Lamiaceae) in Inflammatory Diseases

Ortiz-Mendoza,

Martínez-Gordillo,

Martínez-Ambriz

et al. 2023

Plants

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Abietane‐Type Diterpenoids: Insights into Structural Diversity and Therapeutic Potential

Sargazifar,

Ghorbanian Charami,

Esmaeilzadeh Kashi

et al. 2024

Chemistry & Biodiversity

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The abietane‐type diterpenoids are among the most significant diterpene subsets found in hundreds of plant species belonging to various families. Among which, the members of the genus Salvia and Euphorbia are rich in abietane diterpenoids. Because of the chemical diversity and notable bioactivities, such as anticancer, antiinflammatory, antimicrobial, and antioxidant activities, abietane‐type diterpenoids are attractive. Herein, recent advances in the isolation and characterization of abietane‐type diterpenoids from natural sources, as well as their biological activities, from 2015 up to 2024 are reviewed. During this time, over 300 abietane diterpenoids with diverse structures have been discovered.

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Wood calamint ameliorates ethanol-induced stomach injury in rats by augmentation of hsp/bax and inflammatory mechanisms

Ahmed,

Jabbar,

M.Raouf

et al. 2024

J Mol Histol

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Anti-inflammatory abietanes diterpenes and triterpenoids isolated from Clinopodium polycephalum

Cited by 9 publications

References 12 publications

Ethnobotanical, Phytochemical, and Pharmacological Properties of the Subfamily Nepetoideae (Lamiaceae) in Inflammatory Diseases

Ethnobotanical, Phytochemical, and Pharmacological Properties of the Subfamily Nepetoideae (Lamiaceae) in Inflammatory Diseases

Abietane‐Type Diterpenoids: Insights into Structural Diversity and Therapeutic Potential

Wood calamint ameliorates ethanol-induced stomach injury in rats by augmentation of hsp/bax and inflammatory mechanisms

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