Anti-inflammatory activity of total flavonoids from seeds of &amp;lt;italic&amp;gt;Camellia oleifera&amp;lt;/italic&amp;gt; Abel

Liu, Xiaohui; Jia, Ling-Yan; Gao, Ying; Ли, Бо

doi:10.1093/abbs/gmu071

Cited by 43 publications

(20 citation statements)

References 10 publications

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“…C. oleifera seed is one of the important sources of highquality edible oil in China (And & Yen, 2006). Saponins, oligosaccharides and polysaccharides extracted from C. oleifera seed have many biological effects, such as immunostimulant, hypocholesterolaemic and antimicrobial properties (Liu, Jia, Gao, Li, & Tu, 2014;Ye, Yang, Fang, & Li, 2015), but there were only a few reports on the effects of C. oleifera seed extract in poultry, especially under infections condition.…”

Section: Introductionmentioning

confidence: 99%

Effects of microencapsulated probiotics and plant extract on antioxidant ability, immune status and caecal microflora in Escherichia coli K88-challenged broiler chickens

Dong

Wang

et al. 2019

Food and Agricultural Immunology

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In this study, a total of 180 one-day-old male Arbor Acres broilers were randomly allotted to 5 groups with 6 replicates per group. Birds in negative control group were fed a corn-soybean mealbased diet, and birds in positive control group, MEF group, COSE group, MEF + COSE group were challenged with E. coli K88 and supplemented with 0, 1 × 10 10 cfu MEF/kg of diets, 500 mg COSE/ kg of diets or their combinations, respectively. Results showed that PC group had lower average body weight and greater E. coli counts in caecal contents than NC group. MEF and COSE significantly increased average body weight, serum IgA level, T-SOD activity compared with that of PC group. MEF and MIX group had less caecal E. coli counts than PC birds. The results indicated dietary supplementation of MEF and COSE had a positive moderating effect on E. coli K88-challenged broiler chickens.

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Section: Introductionmentioning

confidence: 99%

Effects of microencapsulated probiotics and plant extract on antioxidant ability, immune status and caecal microflora in Escherichia coli K88-challenged broiler chickens

Dong

Wang

et al. 2019

Food and Agricultural Immunology

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“…More specifically, camellia seed oil enhances the hepatic antioxidant defense system and endogenous or exogenous defense mechanisms in order to achieve the prevention of liver damage, including via the downregulation of aspartate aminotransferase, alanine aminotransferase, and lactate dehydrogenase, as well as the upregulation of antioxidant enzymes, including glutathione peroxidase, glutathione reductase, and glutathione S-transferase 3 . In addition, still other research has shown that the four kaempferol glycosides that can be separated from camellia seed oil exhibit various anti-inflammatory effects, while seamin have antioxidant activity existing methanol distinction of camellia seed oil 4,5 . Camellia seed oil was first recorded as a medical oil in the Compendium of Materia Medica and is recommended as a healthy edible oil by the FAO 6 .…”

Section: Introductionmentioning

confidence: 99%

Quality Characterization and Oxidative Stability of Camellia Seed Oils Produced with Different Roasting Temperatures

et al. 2018

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“…Therefore, it is important to suppress hepatic inflammation in the early stages of liver injury to ameliorate its progression to fibrosis. A previous in vitro study has demonstrated that total flavonoids extracted from C. oleifera possesses the anti‐inflammatory activities by inhibiting iNOS, COX‐2, TNF‐α expression in LPS‐stimulated RAW264.7 cells (Liu, Jia, Gao, Li, & Tu, ). Although the defatted C. oleifera seeds pomace was often discarded without effective utilization, a recent review also summarized that bioactive component from the defatted C. oleifera have potentials in anti‐inflammatory effects (Xiao et al., ).…”

Section: Discussionmentioning

confidence: 99%

Camellia Oleifera Seed Extract Mildly Ameliorates Carbon Tetrachloride‐Induced Hepatotoxicity in Rats by Suppressing Inflammation

Yeh

Huang

et al. 2019

Journal of Food Science

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The objective of this study was to evaluate the effects of a hot‐water extract of defatted Camellia oleifera seeds (CSE) in carbon tetrachloride (CCl4)‐induced liver damage in rats. Wistar rats were separated into four groups including the normal (N) and CCl4 control (C) groups, which are fed a control diet, and the CCL (low‐dose CSE) and CCH (high‐dose CSE) groups, which are fed with a control diet plus different amount of CSE for an 8‐week experimental period. Liver injury in the C, CCL, and CCH groups was induced by injecting CCl4 (i.p.) twice a week from the 5th week to the end of the study. In CCl4‐treated rats, the alanine transaminase (ALT) and aspartate transaminase (AST) activities and malondialdehyde (MDA) concentration significantly increased compared to the normal group. Lower antioxidative enzyme activities and higher proinflammatory cytokines, transforming growth factor‐β (TGF‐β) and hydroxyproline concentrations in the liver were also found in the CCl4‐treated group compared to the normal group. In contrast, the administration of CSE alleviated the biochemical and histopathological changes including inflammation, liver cell damage, and fibrosis caused by CCl4 in rats. Our results indicated that CSE exhibited hepatoprotective effects in CCl4‐induced liver hepatotoxicity through alleviating hepatic inflammation and fibrosis in rats. Practical Application Camellia oleifera are widely used for edible oil production while the defatted seeds pomace is often discarded. We found that extract of C. oleifera pomace containing phenolic compounds, saponins, and polysaccharides showed protective effects chemical‐driven liver damage and, therefore, may be used in further studies and developing functional foods.

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Anti-inflammatory activity of total flavonoids from seeds of <italic>Camellia oleifera</italic> Abel

Cited by 43 publications

References 10 publications

Effects of microencapsulated probiotics and plant extract on antioxidant ability, immune status and caecal microflora in Escherichia coli K88-challenged broiler chickens

Effects of microencapsulated probiotics and plant extract on antioxidant ability, immune status and caecal microflora in Escherichia coli K88-challenged broiler chickens

Quality Characterization and Oxidative Stability of Camellia Seed Oils Produced with Different Roasting Temperatures

Camellia Oleifera Seed Extract Mildly Ameliorates Carbon Tetrachloride‐Induced Hepatotoxicity in Rats by Suppressing Inflammation

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