Anti-inflammatory, analgesic and wound healing activities of the leaves of Memecylon edule Roxb.

Nualkaew, Somsak; Rattanamanee, Kwanchai; Thongpraditchote, Suchitra; Wongkrajang, Yuvadee; Nahrstedt, Adolf

doi:10.1016/j.jep.2008.10.034

Cited by 38 publications

(22 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The anti-inflammatory, analgesic and antioxidant activities of the leaves of Memecylon edule (common names: Kaayam, Delek bangas, Delek air, Miat and Nemaaru), used traditionally in Thailand, were studied. [37] The results of the study provided evidence for the topical use of the leaves of this plant as an anti-inflammatory, analgesic agent and as an antioxidant, in the traditional management of pain and inflammatory diseases and for woundhealing. The efficacy of Hippophae rhamnoides (common name: Sea buckthorn) (SBT) seed oil on burn wound model was investigated.…”

Section: Plants Possessing Both Wound-healing and Antioxidant Propertiesmentioning

confidence: 89%

Wound healing and antioxidant properties: do they coexist in plants?

Süntar

Akkol

Nahar

et al. 2012

Free Radicals and Antioxidants

151

109

View full text Add to dashboard Cite

Section: Plants Possessing Both Wound-healing and Antioxidant Propertiesmentioning

confidence: 89%

Wound healing and antioxidant properties: do they coexist in plants?

Süntar

Akkol

Nahar

et al. 2012

Free Radicals and Antioxidants

151

109

View full text Add to dashboard Cite

“…The chemical constituents (Epigallocatechin gallate, marketing and ellagic acid glycosides) of M. edule were isolated and tested for anti-inflammatory activity. 8 Phytochemical analysis results show the presence of 13 fatty acids, 12 methyl tetradeconate, glucose, amino acids, carotenoids, glycosides and saponins in the genus Memecylon.…”

Section: Introductionmentioning

confidence: 99%

“…5 The leaves of this plant used for the treatment of ophthalmic, leucorrhoea, spasmolysis, gonorrhea and hypoglycaemia 6 and possess anti-inflammatory, analgesic, wound healing and free radical scavenging properties. 7,8 The roots of this plant used as a remedy for excessive menstrual discharge. 9 Root and leaf decoction used for food poisoning and treat urticaria antipruritic in Thai medicine.…”

Section: Introductionmentioning

confidence: 99%

Antioxidant Compound Quercetin-3-O-α-L-rhamnoside(1→6)- β-D-glucose (Rutin) isolated from ethyl acetate leaf extracts of Memecylon edule Roxb (Melastamataceae)

2015

View full text Add to dashboard Cite

Introduction:The present study was aimed to isolate antioxidant principle from leaf ethyl acetate extract of Memecylon edule for the first time. M. edule belongs to melastomataceae family; possess various biological properties and folklore uses. Methods: Isolation of antioxidant compound was carried out by DPPH radicals scavenging activity guided method and employing chromatography techniques (TLC and column chromatography). The structure of isolated bioactive compound (Rutin) was confirmed by using various spectral data like UV, FT-IR, LC-MS, CHNS analysis, 1 H-NMR, 13 C-NMR, DEPT-135, HMBC and HSQC. In vitro antioxidant activity of isolated compound was evaluated by using DPPH radical, nitric oxide radical, superoxide radical, hydroxyl radical scavenging assays and ferric reducing antioxidant power assay (FRAP) with reference to ascorbic acid and butylated hydroxyanisole (BHA). One way analysis of variance (ANOVA) and Tukey's multiple comparison tests were performed. Results: DPPH activity guided isolation resulted isolation of Rutin. Isolated rutin exhibited remarkable scavenging capacity on all tested radicals in a concentration dependent manner. The results also showed that Rutin harbor strong reductive capacity on hydroxyl radicals with lowest IC 50 value (17.06 µg/ml) and strong ferric ion (Fe

show abstract

“…Muitas espécies da família Melastomataceae possuem ação antibacteriana (Wang et al, 2008), hipoglicemiante (Cunha et al, 2008), anti-inflamatória e analgésica (Nualkaew et al, 2009), e algumas espécies são utilizadas no tratamento de dor gástrica e gastrite, dispepsia, verminoses, escabiose e hipertensão (Silva et al, 2000;Cruz, 2004).…”

Section: Introductionunclassified

Caracterização morfoanatômica de folhas e caules de Microlicia hatschbachii Wurdack, Melastomataceae

Cassiano¹,

Branco²,

Silva³

et al. 2010

Rev. bras. farmacogn.

View full text Add to dashboard Cite

RESUMO:Este trabalho apresenta o estudo morfoanatômico das folhas e caules de Microlicia hatschbachii Wurdack, Melastomataceae. Esta espécie possui folhas elípticas a oval-elípticas, margem inteira, ápice agudo e base simétrica e arredondada. A lâmina foliar é anfiestomática, com estômatos do tipo anisocítico e anomocítico, a epiderme é uniestratificada, com células isodiamétricas em secção transversal, e presença de inúmeros tricomas glandulares. O mesofilo é do tipo isobilateral com feixe vascular bicolateral envolvido por algumas células esclerenquimáticas na nervura central. O caule tem secção quadrangular a circular e epiderme unisseriada, com tricomas similares aos da folha. Drusas de oxalato de cálcio foram encontradas nas folhas e no caule. Unitermos: Microlicia hatschbachii, Melastomataceae, morfoanatomia.ABSTRACT: This work shows the morpho-anatomical study of leaf and stem of Microlicia hatschbachii Wurdack (Melastomataceae). Its leaves are elliptic to oval-elliptic, with entire margin, acute apex and rounded symmetrical base. The leaf blade is amphistomatical with anisocytic and anomocytic stomata, in transection the epidermis is uniseriate with isodiametric cells and presence of several glandular trichomes. The mesophyll is isobilateral with bicollateral vascular bundles surrounded by some sclerenchymatic cells in midrib. The stem has a quadrangular to circular transection and uniseriate epidermis with trichomes like ones of leaf. Several druses of calcium oxalate are found in the leaf and stem.

show abstract

Anti-inflammatory, analgesic and wound healing activities of the leaves of Memecylon edule Roxb.

Cited by 38 publications

References 8 publications

Wound healing and antioxidant properties: do they coexist in plants?

Wound healing and antioxidant properties: do they coexist in plants?

Antioxidant Compound Quercetin-3-O-α-L-rhamnoside(1→6)- β-D-glucose (Rutin) isolated from ethyl acetate leaf extracts of Memecylon edule Roxb (Melastamataceae)

Caracterização morfoanatômica de folhas e caules de Microlicia hatschbachii Wurdack, Melastomataceae

Contact Info

Product

Resources

About