Anti-inflammatory Effect of Phyllanthus niruri L. from Indonesia (Pre-clinical Study)

Abstract

At the present, the treatment of inflammation using NSAIDs (non-steroidal anti-inflammatory drugs). Research by Teslim et al, that published in 2014, found there are many side effect of this drugs, among others: high blood pressure, low blood pressure, indigestion, gastro-intestinal bleeding, ulcer, vomiting, diarrhea, abdominal pain, heart attack, kidney disorders, dizziness, comma/ unconsciousness, nausea, constipation, gastric pain and liver problems. 7 Due to many side effects of NSAIDs, many people used medicinal traditional plant to treat pain and inflammation. Currently, there is no study which is reporting on anti-inflammatory effect of effect ethyl acetate fraction of ethanol extract P. niruri L.