Anti-oxidant, anti-inflammatory and anti-cancer activities of avocado (Persea americana) fruit and seed extract

Alkhalaf, Maha I.; Alansari, Wafa S.; Ibrahim, E. M.; Elhalwagy, Manal E.A.

doi:10.1016/j.jksus.2018.10.010

Cited by 98 publications

(67 citation statements)

References 16 publications

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“…Peel antioxidant activity exhibits higher values than the seeds and pulp due to its threefold increased polyphenol content [7]. On the other hand, a lipid extract of the avocado seed exhibited highly powerful anti-inflammatory and anti-cancer effects due to the high percentages of hydrocarbon, sterols and unsaturated fatty acids, mainly oleic acid [52].…”

Section: Avocado Byproductsmentioning

confidence: 99%

High-Value Compounds in Fruit, Vegetable and Cereal Byproducts: An Overview of Potential Sustainable Reuse and Exploitation

et al. 2020

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Food waste (FW) represents a global and ever-growing issue that is attracting more attention due to its environmental, ethical, social and economic implications. Although a valuable quantity of bioactive components is still present in the residuals, nowadays most FW is destined for animal feeding, landfill disposal, composting and incineration. Aiming to valorize and recycle food byproducts, the development of novel and sustainable strategies to reduce the annual food loss appears an urgent need. In particular, plant byproducts are a plentiful source of high-value compounds that may be exploited as natural antioxidants, preservatives and supplements in the food industry, pharmaceuticals and cosmetics. In this review, a comprehensive overview of the main bioactive compounds in fruit, vegetable and cereal byproducts is provided. Additionally, the natural and suitable application of tailored enzymatic treatments and fermentation to recover high-value compounds from plant byproducts is discussed. Based on these promising strategies, a future expansion of green biotechnologies to revalorize the high quantity of byproducts is highly encouraging to reduce the food waste/losses and promote benefits on human health.

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Section: Avocado Byproductsmentioning

confidence: 99%

High-Value Compounds in Fruit, Vegetable and Cereal Byproducts: An Overview of Potential Sustainable Reuse and Exploitation

et al. 2020

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“…Avocado extracts, thanks to their polyphenol content, expressed as gallic acid equivalents, are already used in cosmetic care [21], as well as a means to delay the oxidation of sunflower oil [22]. Moreover, many studies confirm [23][24][25][26] that avocado pit has cytotoxic properties, inter alia, against breast, lung, colon, and prostate cancer cells.…”

Section: Introductionmentioning

confidence: 99%

Compaction Process as a Concept of Press-Cake Production from Organic Waste

et al. 2020

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As a result of agri-food production large amounts of organic waste are created in the form of press cakes. Until now, they were mainly used as animal fodder and also utilized for biofuels production. No other way usage has been found yet. A large quantity of these by-products is usually discarded in open areas, which leads to potentially serious environmental problems. The rich chemical composition of these waste products makes it possible to use them for producing other food products valuable for consumers. Based on the test results obtained, it can be stated that moisture content of press cakes is varied and depends on the input material. However, appropriately composed mixtures of various waste products and a properly conducted compaction process allows for obtaining a new product with functional properties. In addition, application of honey powder and starch tablet coating creates a product of resistant to compression and cutting. Results seem to have commercial importance, as they demonstrate that properly processed by-products can be used in food preparations as dietary supplements.

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“…Similarly, the presence of oleic acid and sterol compounds in chloroform/methanol extract of seeds was responsible for the anti‐inflammatory and anticancer activities in a cell line for colon cancer (HCT116) and for liver cancer (HePG2) and this in a dose‐dependent manner. It also exhibited powerful scavenging of free radicals by using the DPPH· and ABTS methods (Alkhalf, Alansari, Ibrahim, & Elhalwagy, ). In a similar study, Abubakar, Achmadi, and Suparto () reported that a triterpenoid isolated from an ethanolic extract of avocado seed showed a significant cytotoxic activity against all investigated cell lines (Vero cell line (ATCC CCL‐81), human breast cancer cell line MCF‐7 (ATCC HTB‐22), and human liver cancer cell line HepG2 (ATCC HB‐8065)).…”

Section: Wastes and Byproducts From Tropical Fruits And Their Currentmentioning

confidence: 99%

Valorization of byproducts from tropical fruits: Extraction methodologies, applications, environmental, and economic assessment: A review (Part 1: General overview of the byproducts, traditional biorefinery practices, and possible applications)

Villacís-Chiriboga

Elst

Camp

et al. 2020

Comp Rev Food Sci Food Safe

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Tropical fruits represent one of the most important crops in the world. The continuously growing global market for the main tropical fruits is currently estimated at 84 million tons, of which approximately half is lost or wasted throughout the whole processing chain. Developing novel processes for the conversion of these byproducts into value‐added products could provide a viable way to manage this waste problem, aiming at the same time to create a sustainable economic growth within a bio‐economy perspective. Given the ever‐increasing concern about sustainability, complete valorization through a bio‐refinery approach, that is, zero waste concept, as well as the use of green techniques is therefore of utmost importance. This paper aims to report the status on the valorization of tropical fruit byproducts within a bio‐refinery frame, via the application of traditional methodologies, and with specific attention to the extraction of phenolics and carotenoids as bioactive compounds. The different types of byproducts, and their content of bioactives is reviewed, with a special emphasis on the lesser‐known tropical fruits. Moreover, the bioactivity of the different types of extracts and their possible application as a resource for different sectors (food, pharmaceutical, and environmental sciences) is discussed. Consequently, this review presents the concepts of tropical fruit biorefineries, and the potential applications of the isolated fractions.

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Anti-oxidant, anti-inflammatory and anti-cancer activities of avocado (Persea americana) fruit and seed extract

Cited by 98 publications

References 16 publications

High-Value Compounds in Fruit, Vegetable and Cereal Byproducts: An Overview of Potential Sustainable Reuse and Exploitation

High-Value Compounds in Fruit, Vegetable and Cereal Byproducts: An Overview of Potential Sustainable Reuse and Exploitation

Compaction Process as a Concept of Press-Cake Production from Organic Waste

Valorization of byproducts from tropical fruits: Extraction methodologies, applications, environmental, and economic assessment: A review (Part 1: General overview of the byproducts, traditional biorefinery practices, and possible applications)

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