Anti-Photoaging Effect of Plant Extract Fermented with Lactobacillus buchneri on CCD-986sk Fibroblasts and HaCaT Keratinocytes

Kang, Yun‐Mi; Hong, Chul-Hee; Kang, Seungwoo; Seo, Dong-Seok; Kim, Seong‐Oh; Lee, Hoon-Yeon; Sim, Hyeon-Jae; An, Hyo‐Jin

doi:10.3390/jfb11010003

Cited by 28 publications

(23 citation statements)

References 35 publications

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“…In vitro study of the effects of plant extracts fermented with Lactobacillus buchneri (PELB) on ultraviolet light (UVB)-induced photoaging process reported that PELB could be useful in the cosmetic industry due to its protective effects against UVB-induced photoaging. PELB works by decreasing elastase activity and increasing type I collagen expression, reducing collagenase activity, and promoting the expression of moisture factor and antioxidant enzymes ( 29 ). Our study product showed a significant and persisting increase in skin elasticity which was expressed in the first two weeks of product application.…”

Section: Discussionmentioning

confidence: 99%

The Moisturizing Efficacy of a Dermo-Cosmetic Product (cls02021) Versus in a 6-week Application Period

Catic¹,

Pehlivanovic²,

Pljakic³

et al. 2022

Med Arch

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Background: Studies suggest that applying probiotic skincare products may have beneficial effects on the skin due to bacteria competitiveness and specific metabolites produced by probiotics. The cream CLS02021 is a postbiotic blend of metabolites, including organic acids, enzymes, and peptides that are a result of the co-fermentation of three proprietary probiotic strains and is specific for its high concentration of the enzyme Sphingomyelinase which plays a significant role in cell signaling pathways and ceramide production. Objective: The aim of this study is to evaluate the cosmetic effects of probiotic-derived Ingredient CLS02021 and its safety in healthy volunteers. Methods: Fifty healthy volunteers between 18 and 69 years old were recruited to participate in this multicentric, randomized, intra-individual, double-blind group study. Following a face-split design, volunteers applied both face cream containing CLS02021 on one side of their face and a placebo cream on the other side of their face for a total duration of four weeks, two times a day. Evaluation of the cosmetic effects included instrument measurements of moisturizing, elasticity, wrinkle depth, sebum production, pore size, melanin production, sensitivity, and side effects. Results: A significant difference of CLS02021 over the placebo group was observed for moisture and elasticity increase (both p<0.001), pore size (p<0.01), and a wrinkle depth decrease (p<0.05). No significant differences were noted in sebum production, melanin level, skin cleanliness, and sensitivity between groups. Conclusion: CLS02021, as a probiotic-derived ingredient, showed strong beneficial effects on skin moisture and elasticity increase, wrinkle depth, and pore size reduction. Face cream containing CLS02021 is well tolerated and could be an organic choice for cosmetic hydrating and antiaging skincare treatment.

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Section: Discussionmentioning

confidence: 99%

The Moisturizing Efficacy of a Dermo-Cosmetic Product (cls02021) Versus in a 6-week Application Period

Catic¹,

Pehlivanovic²,

Pljakic³

et al. 2022

Med Arch

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“…The soybean milk fermented by the B. breve strain has a significant increase in hyaluronic acid (HA) production, as demonstrated in a cellular test on skin cells (keratinocytes). Hyaluronic acid, which contributes to skin hydration and elasticity, is naturally produced in human keratinocytes and fibroblasts [24,25]. The B. breve Yakult strain has the ability to convert isoflavone glycoside from soya into aglycone via βglucosidase [26,27].…”

Section: Soybeanmentioning

confidence: 99%

Biological and Cosmetical Importance of Fermented Raw Materials: An Overview

Majchrzak¹,

Motyl²,

Śmigielski³

2022

Preprint

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The cosmetics industry is currently looking for innovative ingredients with higher bioactivity and bioavailability for the masses of natural and organic cosmetics. Bioferments are innovative ingredients extracted from natural raw materials by carrying out a fermentation process with appropriate strains of microorganisms. The review was conducted using the SciFinder database with the keywords fermented plant, cosmetics, fermentation. Mainly bioferments are made from plant-based raw materials. The review covers a wide range of fermented raw materials from waste materials (whey with beet pulp) to plant oils (F-Shiunko, F-Artemisia, F-Glycyrrhiza). The spectrum of applications for bioferments is broad and includes properties such as skin whitening, antioxidant properties (blackberry, soybean, goji berry), anti-ageing, anti-aging (red ginseng, black ginseng, Citrus unshiu peel), hydrating and anti-allergic (aloe vera, skimmed milk). Fermentation increases the biochemical and physiological activity of the substrate by converting high-molecular compounds into low-molecular structures, this makes fermented raw materials more compatible compared to unfermented raw materials.

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“…They found that PELB decreased elastase activity and increased type I collagen expression in the UVB-induced photoaging in vitro model, reduced collagenase activity, and promoted the expression of moisture factor and antioxidant enzymes. The study results show that the PELB could be useful in the cosmetic industry due to its protective effects against UVB-induced photoaging [ 26 ]. Notay et al investigated the use of topical Nitrosomonas eutropha for cosmetic improvement of facial wrinkles.…”

Section: Photoaging and Skin Agingmentioning

confidence: 99%

Topical Probiotics in Dermatological Therapy and Skincare: A Concise Review

França

2020

Dermatol Ther (Heidelb)

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Recent studies have produced an increasing body of evidence that the intestinal microbiome plays an essential role in modulating systemic inflammation and skin diseases. The gut microbiome influences and modulates the host immune system, enabling immune tolerance of environmental and dietary antigens and protecting against pathogens. Emerging scientific evidence has demonstrated that oral probiotics can help treat certain skin diseases, such as acne, atopic dermatitis, photoaging, psoriasis, and wound healing. The aim of this paper is to review the current scientific evidence on topical probiotics and their effects on dermatological diseases and skincare and to clarify if the application of exogenous probiotics could also have the same benefit as oral probiotics in promoting positive bacterial balance to treat dermatologic conditions.

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Anti-Photoaging Effect of Plant Extract Fermented with Lactobacillus buchneri on CCD-986sk Fibroblasts and HaCaT Keratinocytes

Cited by 28 publications

References 35 publications

The Moisturizing Efficacy of a Dermo-Cosmetic Product (cls02021) Versus in a 6-week Application Period

The Moisturizing Efficacy of a Dermo-Cosmetic Product (cls02021) Versus in a 6-week Application Period

Biological and Cosmetical Importance of Fermented Raw Materials: An Overview

Topical Probiotics in Dermatological Therapy and Skincare: A Concise Review

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