Anti-thyroid-stimulating hormone receptor antibodies determined by second-generation assay

Mankaï, Amani; Toumi, Dorsaf; Chadli-Chaieb, M.; Ghedira-Besbes, Leila; Saad, F.; Ouertani, Mohamed Zied; Jeddi, M.; Chaieb, L.; Ghedira, Ibtissem

doi:10.1515/cclm.2007.016

Cited by 6 publications

(1 citation statement)

References 14 publications

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“…We considered 21 articles eligible [18,[20][21][22][23][26][27][28]30,[32][33][34][35][36][37][38][39][40][41][42][43] and subdivided them in 4 groups, depending on the type of TRAb assay employed: h2G (11 records), p2G (6 records), m3G (5 records), a3G (7 records). We did not consider in the control group patients with other autoimmune thyroid diseases (i.e.…”

Section: Methodsmentioning

confidence: 99%

TSH receptor autoantibody immunoassay in patients with Graves' disease: Improvement of diagnostic accuracy over different generations of methods. Systematic review and meta-analysis

Tozzoli¹,

Bagnasco²,

Giavarina³

et al. 2012

Autoimmunity Reviews

166

104

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Section: Methodsmentioning

confidence: 99%

TSH receptor autoantibody immunoassay in patients with Graves' disease: Improvement of diagnostic accuracy over different generations of methods. Systematic review and meta-analysis

Tozzoli¹,

Bagnasco²,

Giavarina³

et al. 2012

Autoimmunity Reviews

166

104

View full text Add to dashboard Cite

Levels of cytokines and thyroid autoantibodies in Omani patients with Graves’ disease

Alnaqdy¹,

Al-Maskari

2007

British Journal of Biomedical Science

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Frequency of antithyroid antibodies in patients with primary biliary cholangitis

Ghozzi,

Mankai,

Chedly

et al. 2023

Laboratory Medicine

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Objective Primary biliary cholangitis (PBC) is an autoimmune disease of liver that may be associated with other conditions, including autoimmune thyroid diseases. We aimed to investigate the frequency of anti-thyroperoxidase antibodies (TPO-Ab), antithyroglobulin antibodies (TG-Ab), and anti–thyrotropin receptor antibodies (TSHR-Ab) in Tunisian patients with PBC. Methods Sera of 80 patients with PBC were collected over a 9-year period. A total of 189 healthy blood donors (HBD) were included in the control group. Measurements of TPO-Ab and TG-Ab were performed using indirect enzyme-linked immunosorbent assay (ELISA). Competitive ELISA was used to assess TSHR-Ab. Results Antithyroid antibodies (ATA) were significantly more frequent in PBC patients than in the control group (13.7% vs 1.6%; P < 10−3). Out of 11 patients with ATA, 10 (90.9%) were female. Nine patients and 2 HBD had TPO-Ab (11.2% vs 1%; P < 10−3). TG-Ab were more frequent in patients than in healthy subjects but the difference was not statistically significant (6.2% vs 1.6%; P = .1). TPO-Ab and TG-Ab were present together in 3 patients (3.7%). TSHR-Ab were absent in patients and controls. Conclusion This study shows that PBC is associated with a high frequency of ATA but not TG-Ab or TSHR-Ab.

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Anti-thyroid-stimulating hormone receptor antibodies determined by second-generation assay

Abstract: TRAb, but neither TPO-Ab nor TG-Ab, is valuable in the diagnosis and management of patients with GD.

Cited by 6 publications

References 14 publications

TSH receptor autoantibody immunoassay in patients with Graves' disease: Improvement of diagnostic accuracy over different generations of methods. Systematic review and meta-analysis

TSH receptor autoantibody immunoassay in patients with Graves' disease: Improvement of diagnostic accuracy over different generations of methods. Systematic review and meta-analysis

Levels of cytokines and thyroid autoantibodies in Omani patients with Graves’ disease

Frequency of antithyroid antibodies in patients with primary biliary cholangitis

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