Antibacterial Activities of Et-OH Extract from Extruded White Ginseng on Tooth Decay Bacteria

손현정,; 한민수,; 류기형,

doi:10.3746/jkfn.2009.38.7.951

Cited by 7 publications

(5 citation statements)

References 2 publications

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“…11.00 ± 0.00 de 50.00 100.00 (1) Diameter of inhibition zone. Values represent the mean of triplicates ± SD, including the diameter of the paper disc (6 mm) (2) Non-heat-treated ginseng (3) Means with different uppercase and lowercase letters in the same column are significant differences (p \ 0.05) Similar results were obtained in a previous study, which showed that the antimicrobial activity of a ginseng extract decreased as the number of bacteria increased according to the disc diffusion method [33].…”

Section: Growth Inhibitory Effects Of Ginseng Extractssupporting

confidence: 75%

Enhancing the antimicrobial activity of ginseng against Bacillus cereus and Staphylococcus aureus by heat treatment

Kim

Rhee

et al. 2017

Food Sci Biotechnol

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This study evaluated the antimicrobial activities [diffusion inhibition zone, minimum inhibitory concentration (MIC), and minimum bactericidal concentration], of heated ginseng extracts (ethanol and methanol). The extract yields, ginsenoside compositions, growth inhibitory effects against and and bacterial cell membrane potential changes, were also investigated. Methanol extracts of heated ginseng, showed higher antimicrobial activity than ethanol extracts. was more easily inhibited than. Ginseng heated at 100 °C for 2 and 16 h, showed maximum antimicrobial activity against and, respectively. In the growth inhibitory test, and were completely inhibited after 2 and 8 h culture at the MIC. The cell membrane potential decreased with increasing concentration of extract, indicating cell metabolism disruption. Ginsenosides Rg, a potent antibacterial substance, which were absent in non-heated ginseng, were produced by heating ginseng at 100 °C for 4 and 8 h, respectively.

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Section: Growth Inhibitory Effects Of Ginseng Extractssupporting

confidence: 75%

Enhancing the antimicrobial activity of ginseng against Bacillus cereus and Staphylococcus aureus by heat treatment

Kim

Rhee

et al. 2017

Food Sci Biotechnol

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“…PC extracts and 8 extracts of 3 other plants (Syzygium aromaticum, 31 S. aromaticum, 32 and ginseng berry, 33 previously reported as having antimicrobial effects, were subjected to antimicrobial activity measurement using the disc diffusion method. Only the PC extracts showed antibacterial activity, and the ethanol extract showed higher antibacterial activity than the hot-water extract.…”

Section: Comparison Of the Antimicrobial Activity Of Pc Extracts And Other Plant Extracts Against S Mutans (Kctc 3065)mentioning

confidence: 99%

Antimicrobial and Anti-Inflammatory Effects of the Ethanol Extract of Polygonum cuspidatum as a Mouthwash Component

Kim

et al. 2021

Natural Product Communications

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Polygonum cuspidatum (PC) has been used as traditional Korean medicine to treat various diseases including asthma, hypertension, cancer, and arteriosclerosis. In this study, we assessed the antibacterial and anti-inflammatory effects of PC ethanol extract. Persistent antibacterial activity against Streptococcus mutans for up to 23 days was observed when the extract was used at a concentration of 10 mg/mL. The minimum inhibitory concentration of PC against S. mutans was 0.2 mg/mL and the minimum bactericidal concentration was 10 mg/mL. We compared the antimicrobial activities of S. mutagens cultured with or without PC. Bacterial activity was observed only in the group where RE was not added. The anti-inflammatory effect of PC on RAW264.7 cells was assessed using the MTT assay; changes in nitric oxide (NO) production and inflammatory cytokine levels (tumor necrosis factor [TNF]-α and interleukin [IL]-6) were measured in the presence of PC. In lipopolysaccharide-induced RAW264.7 cells, PC inhibited NO production by 68.6% when used at a concentration of 50 µg/mL. The expression of TNF-α and IL-6 was reduced by PC in a concentration-dependent manner. These results suggest that the ethanol extract of PC could be used as a mouthwash component with antibacterial and anti-inflammatory effects.

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“…여러가지 생리활성 성분의 존재가 알려져서 오랫동안 한약재 와 건강기능식품으로 사용되고 있는 인삼(Panax ginseng)과 충 치 원인균인 S. mutans에 대하여는 사포닌을 함유한 홍삼 에탄 올 추출물이 S. mutans의 생육을 저해하며[minimum inhibitory concentration (MIC)=150 mg/mL] [16], 지용성의 홍삼박 n-hexane 추출물[n-hexane extract of red ginseng marc (HERGM)]이 S. mutans의 생육(MIC=125 μg/mL), 균체 부착 및 생물막 형성을 저해 [17]한다는 결과가 있다. 또한 HERGM과 L-arginine을 병 용하면 S. mutans 생육 저해에 시너지 효과를 보였으며, 이는 주로 HERGM이 기여하는 것으로 조사 [18]되었다.…”

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Combined effects of L-arginine and n-hexane extract from Korean red ginseng marc on biofilm formation of Streptococcus mutans

Kim,

2024

JABC

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In this study, the combined effects of lipid-soluble nhexane extract of red ginseng marc (HERGM) and water-soluble L-arginine, which has been reported to have anticaries activities, on biofilm formation and glucosyltransferase (Gtase) activity of S. mutans were investigated by checkerboard assay method. The combination of HERGM and L-arginine showed additive effects on both inhibition of biofilm formation and GTase activity of S. mutans with a fractional inhibitory concentration index of 0.75, respectively. When HERGM and L-arginine were treated together, the inhibition of biofilm formation was mainly attributed to Larginine, and the inhibition of GTase activity was attributed to HERGM. These results indicate that L-arginine and HERGM complementarily inhibits the biofilm formation of S. mutans.Keywords L-arginine · Biofilm inhibition · Glucosyltransferase · n-hexane extract of red ginseng marc · Streptococcus mutans 서 론

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Antibacterial Activities of Et-OH Extract from Extruded White Ginseng on Tooth Decay Bacteria

Cited by 7 publications

References 2 publications

Enhancing the antimicrobial activity of ginseng against Bacillus cereus and Staphylococcus aureus by heat treatment

Enhancing the antimicrobial activity of ginseng against Bacillus cereus and Staphylococcus aureus by heat treatment

Antimicrobial and Anti-Inflammatory Effects of the Ethanol Extract of Polygonum cuspidatum as a Mouthwash Component

Combined effects of L-arginine and n-hexane extract from Korean red ginseng marc on biofilm formation of Streptococcus mutans

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