Antibacterial Activities of the Ethanolic Extract of <i>Crateva adansonii</i> DC. (Capparidaceae) Harvested in Dassa-Zoumè in Central Bénin

Abstract

Objective: The present was initiated to study the antibacterial properties of the Crateva adansonii DC extract on germs commonly identified in skin and digestive infections in Benin as well as the reversion of resistance to these aforementioned germs. Method: The bacteria's sensitivity test to extracts was carried out by the microdilution method in liquid medium as well as the MIC and the reversion of bacterial resistance. For the determination of the MBC, this technique is used coupled with spreading on agar medium. Results: The results show an antibacterial activity of the extract with MICs between 0.625 -5 mg/ml. The CMB of Enterococcus faecalis ATCC 29212 is 2.5 mg/ml while that of Methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis CIP 8039 is 5 mg/ml. The reversion of bacterial resistance has shown a synergy of action between our extract and conventional antibiotics.

Antibacterial Properties of <i>Crateva adansonii</i> (Capparidaceae) on Strains Isolated from Chronic Wounds Diagnosed in the Commune of Ouinhi in 2021

“…Characterisation of the antibacterial effect of Crateva adansonii (Capparidaceae) revealed that the aqueous mixture had a bactericidal effect on all the strains tested. This result differs from those obtained by [7] who, using the same plant, had indeterminate, bacteriostatic and bactericidal effects respectively on 50%, 25% and 25% of the germs tested.…”

“…It also contains secondary metabolites such as total tannins, total flavonoids and total phenolics in varying proportions, and has antioxidant properties that vary according to the concentration of the extract [4] [5]. Research by [5] [6] [7] has also shown that Crateva adansonii has antibacterial properties against germs commonly identified in skin and digestive disorders, such as Escherichia coli, Staphylococcus aureus, Proteus mirabilis and Pseudomonas aeruginosa. In Benin, Crateva adansonii is used to treat arterial hypertension [6], diarrhoeal diseases [8] and diabetes in pregnant women in Cotonou [9].…”