Antibacterial activity and mutagenicity studies of water-soluble phosphazene high polymers

Crosslinking Reactions for the Conversion of Polyphosphazenes into Useful Materials

“…Moreover, it is a process that converts ordinary polymer surfaces to blood-or tissue-compatible interfaces that may also discourage colonization by microorganisms. 86 …”

Synthesis and characterization of oxime‐bearing hexakis(2‐formylphenoxy)‐phosphazene and its derivatives

“…The aldehyde proton for 2 appears at 9.96 ppm. The azomethine protons for 3, 4, 5, 6, 7, 8, 9, and 10 are observed at 8 ) ppm, respectively. The azomethine protons are shifted to the lower down field region for compounds 4-10 than for 3.…”

Synthesis of oxime bearing cyclophosphazenes and their reactions with alkyl and acyl halides

“…of 4-hydroxybenzaldehyde and 4-hydroxyacetophenone in the presence of K 2 CO 3 in THF gave hexakis(4-formylphenoxy)cyclotriphosphazene (2) and hexzakis-(4-acetylphenoxy)cyclotriphosphazene (7). Oxime compounds hexakis(4-[(hydroxyimino)methyl]-phenoxy)cyclotriphosphazene (3) and hexakis(4-[(1)-N-hydroxyethaneimidoyl]phenoxy)cyclotriphosphazene (8) were synthesized from the reactions of 2 and 7 with hydroxlaminehydrochloride in pyridine, respectively.…”

“…These compounds are reported to possess interesting biomedical properties and promising applications [6][7][8]. Phosphazene polymers bearing flouralkoxy or aryloxy groups stimulated considerable interest in the past as biologically inert, water insoluble, polymers for blood vessel or heart valve construction [9].…”