Antibacterial Activity for Acne Treatment through Medicinal Plants Extracts: Novel Alternative Therapies for Acne

Abstract

Acne vulgaris is a chronic skin infection affecting the majority of adults. There are several internal and external factors responsible for this infection. The present study emphasizes the screening and combinations of medicinal plants extracts against acne-causing bacteria and antibacterial activity of these plant extracts. Antibacterial activities of three solvents extracts of Camellia sinensis, Azadirachta indica, and Cassia acutifolia was carried out using disc diffusion method against Propionibacterium acnes, Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa, Escherichia coli and Bacillus subtilis. The results revealed that different plant extracts showed noticeable activity against different test organisms. The acetone extract of combination A (C/A) showed the higher mean of antibacterial susceptibility against six bacterial strain with synergistic effect by 20.33mm than other combinations when combination A (C/A) was added. The antimicrobial susceptibility of combination A (C/A) was higher than combination group at concentration of 10 -2 with 95% confidence interval. The present study concluded that the acetonic extract of C/A was the best antibacterial agent/candidate to treat acne vulgaris disease. Further trials might confirm its best possible doses for prescription to the dermatologists, physicians and clinicians in the field.

Culture-sensitivity tests for otitis media diagnosed causative bacteria in Kirkuk province

“…Inoculate the MR-VP medium with bacteria and incubate at 37 ° C for 24 hours, and add 5 drops of the methyl reagent to the medium. The result is positive when a red appears on the surface of the medium (14).…”

“…Indol test: Inoculate the liquid peptone water with isolates, incubate at 37 ° C for 24 hours, add 0.5 ml of Kovacs reagent to the incubated tube and shake lightly. The appearance of a red ring on the surface of the medium indicates a positive result (14).…”

Pattern of antibiotics sensitivity of bacteria causing surgical site infections in several hospitals in Kirkuk- Iraq

“…The collected samples were transferred to the laboratory at the Northern Technical University. They were bred from wound samples on sterile nutrient agar plates and incubated at 37 ° C for 24 hours, then discovered, cultured on an agar diagonal, partly determined against the Gram reaction and kept at 4 ° C in a coolant until use [6].…”

“…[5] Indirect costs are also important, which include reduced productivity and quality of life. As our percentage of older people grows, the frequency and importance of chronic wounds and wound infections increase [6].…”

“…Chronic wounds may not heal or it may take years to do so. These wounds caused patients severe psychological and physical stress, as well as creating a significant financial burden on patients and the health care system as a whole [6]. The risk of surgical wound complications is greater for those over the age of 65, or who suffer from pulmonary disease, undernourishment, overweight, other diseases and high blood pressure [7].…”