Present study attempted to determine the antimicrobial activity of extracts from commonly consumed fruits including guava (Psidium guajava), malta (Citrus sinensis), apple (Malus domestica), orange (Citrus reticulate) and dragon fruit (Hylocereus polyrhizus) against Bacillus spp., Pseudomonas spp., Vibrio spp., Escherichia coli, Klebsiella spp., Staphylococcus spp., Listeria spp., Salmonella spp., and Aeromonas spp. Of the fruits examined, malta and orange samples were observed to be most effective against the test organisms, whereas dragon fruit was the least effective one. Among all the bacteria tested, Bacillus spp. seemed to be most susceptible to the antibacterial activity of the fruits, whereas Aeromonas spp. seemed to be the most resistant one. No significant difference in antimicrobial activity was observed among the imported and local fruit extracts.