Antibacterial activity of embelin

Embelin as a Potential Drug Molecule: A Review

“…Furthermore, herbal monographs (of M/s Himalayan Drugs Company, Bengaluru) suggested that embelin is primarily effective against tapeworm and not roundworm or hookworm. The nematocidal activity of embelin has been explained by Mojumder and Mishra [53][54][55][56] against root-knot nematode (Meloidogyne incognita) with 90% mortality after exposure for 48 h (at 100 ppm concentration level). E. ribes seed oil demonstrated effective activity against Pheretima posthuma compared to standard piperazine citrate (10 mg/ml) was reported by Jalalpure et al…”

“…Embelin is a natural hydroxy benzoquinone with alkyl substitution and is considered as one of the main constituents of plant Embelia ribes (family: Myrsinaceae) [1,2]. Embelin is known to possess various biological activities which mainly include anxiolytic, anticonvulsant, antidepressant, antidiabetic, wound healing, anthelmintic, antimicrobial, antitumor, chemopreventive, antioxidant, antifertility etc.…”

Impact of Population Structure, Growth Habit and Seedling Ecology on Regeneration of <i>Embelia ribes</i> Burm. f. —Approaches toward a Quasi <i>in Situ</i> Conservation Strategy

“…The main active medicinal component in dried fruits of E. ribes is embelin (2, 5-dihydroxy-3-undecyl-2,5-cyclohexadiene-1,4-benzoquinone). This highly valuable medicinal plant has been shown to have antihelmintic [3], antifertility [4,5], antibacterial [6], antidiabetic [7], antitumor, analgesic, antiinflammatory [8,9], antispermatogenic [10], chemopreventive [11] and cardioprotective [12] properties, besides antioxidant activity against methionine-induced hyperhomocysteinemia and hyperlipidemia and oxidative stress in the brain [13].…”

Synthesis and Antibacterial Screening of Novel Derivatives of Embelin

“…The undecyl substituent in embelin confers solubility in the non-polar phase and assists in cell permeability. It exhibits a wide spectrum of biological and physiological activities viz., anthelmintics, antifertility, antitumour, antimicrobial, analgesic, antiinflammatory, anti-implantation and antibacterial activity [5][6][7][8][9][10]. Embelin possesses beneficial effects against oxidative tissue damage [11][12][13].…”