Antibacterial activity of novel Cu₂ZnSnS₄ nanoparticles against pathogenic strains

Abstract

Hollow tubular Cu2ZnSnS4 (CZTS) particles are prepared by heating an ethylene glycol solution of CuCl2, ZnCl2, SnCl4, and thiourea in a molar ratio of 2:1:1:4.5 (215 °C, 6 h).

<p>Biosynthesis of Silver Nanoparticles from <em>Melia azedarach</em>: Enhancement of Antibacterial, Wound Healing, Antidiabetic and Antioxidant Activities</p>

“…The NPs permeate through the bacterial cell wall and interact with cellular contents to disrupt thus resulting in total cellular destruction leading to cell apoptosis. Formation of reactive oxygen species results in the destruction of cell wall components such as deoxy ribonucleic acid, lipids and proteins; once the cell wall ruptures the cytoplasmic fluids flow out 38. Electrostatic interaction between opposite charges can be the mechanism for antibacterial activity of AgNPs.…”

Novel antibacterial application of photovoltaic Cu2SnS3 (CTS) nanoparticles

“…† As seen from Table 1, the bacteria leading to their death; and (2) reactive oxygen species (ROS) are formed, which damage DNA, proteins and lipids in the cell wall, causing its breakdown, leading to leakage of cytoplasmic uid. 15,18,19 However, in the antibacterial activity of CTS nanoparticles, we propose a mechanism based on the electrostatic interaction between opposite charges (Fig. 7).…”

“…[10][11][12][13][14] Recently, the antibacterial activity of CZTS against Grampositive and Gram-negative bacteria has been demonstrated, indicating the high activity of the material against bacterial growth. 15 The specic advantages of these inorganic materials for antibacterial application are the use of non-toxic earthabundant materials and the fact that they are synthesized using simple methods. Also, these materials contain elements that are important for metabolic activity in humans.…”

“…Also, these materials contain elements that are important for metabolic activity in humans. 15 The human body is composed of various major elements like O 2 , N 2 , S and trace elements like Cu, Zn, Sn, etc. The human body contains roughly 75 mg of Cu, which acts as a catalyst in the formation of melanin for pigmentation of skin and has an active role in the repair of tissues.…”

“…Earlier studies have demonstrated that materials containing Cu, Zn, Sn and S in small quantities showed a negligible negative effect on the human body but a greater effect on bacteria. [15][16][17] Hence, the non-toxic nature of these inorganic elements combined with the low elemental cost makes them effective for biocidal applications. Inspired by these facts, in the current study, we have successfully demonstrated for the rst time the antibacterial activity of CTS against pathogenic strains, and a plausible mechanism for the antibacterial activity of CTS nanoparticles is discussed.…”