Antibacterial activity of two MTA‐based root canal sealers

Morgental, Renata Dornelles; Vier-Pelisser, Fabiana Vieira; Oliveira, Sı́lvia Dias de; Antunes, Fernanda Camargo; Cogo, Deborah Meirelles; Kopper, Patrícia Maria Poli

doi:10.1111/j.1365-2591.2011.01931.x

Cited by 116 publications

(120 citation statements)

References 35 publications

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“…Such discrepancies are probably due to methodology. [9] The antimicrobial activity of MTA was reported by Torabinejad et al, who detected its efficiency against some facultative bacteria; however, no activity was found against E. faecalis, Staphylococcus aureus, Bacillus subtilis, and Escherichia coli or against anaerobic bacteria.…”

Section: Discussionmentioning

confidence: 99%

“…It has high radioopacity, low solubility, low expansion during setting, promotes deposition of hard tissue and known for its antibacterial effect. [9] Real Seal SE (SybronEndo, Orange, CA) is fourth generation methacrylate resin based sealer, in that they have further eliminated the separate etching/ bonding step. [10] Acroseal (Septodont, St. Maurdes-Fosses Cedex, France) is calcium hydroxide-based sealer, it appears to have lower solubility than other calcium hydroxide sealers, probably because of its epoxy resin component.…”

Section: Introductionmentioning

confidence: 99%

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Antimicrobial Activity of MTA Fillapex, Real Seal SE, Acroseal and Zinc oxide Eugenol Sealers against Enterococcus Faecalis and Candida Albicans

Rahman¹,

Chandra²,

Chowdhary³

et al. 2017

IOSR JDMS

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Antimicrobial Activity of MTA Fillapex, Real Seal SE, Acroseal and Zinc oxide Eugenol Sealers against Enterococcus Faecalis and Candida Albicans

Rahman¹,

Chandra²,

Chowdhary³

et al. 2017

IOSR JDMS

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“…14,15 When evaluated in suspension with the crushed cement, the MTA Fillapex presented high alkaline pH values. 9 However, when immediately evaluated after mixing, the aforementioned pH value was significantly lower than ordinary gray or white MTA. 16 Nonetheless, there are no comparative studies with other routinely used cements for root canal filling.…”

Section: Jcdpmentioning

confidence: 99%

“…MTA Fillapex presents effective antimicrobial activity against E. faecalis before setting, but not after setting, despite its high pH level. 9 Its bond strength to radicular dentin exhibits the lowest values when compared with another MTA-based cement (I Root SP). 10 Although the MTA Fillapex manufacturer claims that it has excellent radiopacity, easy handling and long working time, their physicochemical properties, such as flow and setting time are scientifically unknown.…”

Section: Mta Fillapexmentioning

confidence: 99%

Evaluation of the Physicochemical Properties and Push- Out Bond Strength of Mta-based Root Canal Cement

Chávez-Andrade¹,

Kuga²,

Duarte³

et al. 2013

The Journal of Contemporary Dental Practice

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Aim: This study investigated the flowability, setting time, pH, calcium release and bond strength of a MTA-based cement (MTA Fillapex ® ) compared to AH Plus and Sealapex. Materials and methods:For the flowability test, the ISO 6876:2001 specification was utilized and for the setting time test, the ASTM C266-03 specification was utilized. For the pH and calcium release measurements, 10 samples were prepared for each group and analyzed for several different periods. For the push-out test, dentin disks were distributed into three groups, according to the cement utilized and into three subgroups, according to the root third (n = 10). After obturation, the specimens underwent push-out testing. The data were compared statistically using a significance level of 5%. Results:The flowability of all materials was found to be similar (p > 0.05). The setting times were different among the groups tested (MTA Fillapex < Sealapex < AH Plus) (p < 0.05). At days 7 and 28, the MTA Fillapex presented the higher pH values (p < 0.05). At 24 hours and at 14 days, the calcium release of the MTA Fillapex was similar to that of Sealapex (p > 0.05). AH Plus presented the lowest pH and calcium release values (p < 0.05). In all root thirds, the adhesion to the dentin of the MTA Fillapex and Sealapex were significantly lower than that of AH Plus (p < 0.05). Conclusion:MTA Fillapex and Sealapex presented several similar properties and both were found to be different than AH Plus.Clinical significance: This study evaluated the physicochemical and mechanical properties of new MTA-based root canal cement, in order to use this scaler in root canal fillings. MTA Fillapex showed satisfactory properties for clinical use.

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“…MTA Fillapex is also biocompatible (9) and has antibacterial activity (10). However, the sealing ability of MTA Fillapex is variable (11,12).…”

Section: Introductionmentioning

confidence: 99%

Effect of the smear layer on apical seals produced by two calcium silicate-based endodontic sealers

et al. 2014

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We compared the apical seals of two new calcium silicate-based sealers (iRoot SP and MTA Fillapex) in the presence and absence of a smear layer. Eighty-two human premolars were prepared and randomly divided into four groups. In groups 1 and 3, the smear layer was retained. In groups 2 and 4, the root canals were irrigated with EDTA to remove the smear layer. Canals were filled using gutta-percha/iRoot SP (in groups 1 and 2) or obturated with gutta-percha/MTA Fillapex (in groups 3 and 4). Fluid filtration was used to evaluate apical microleakage. The presence of the smear layer had no significant effect on the sealing properties of the filling materials, except for iRoot SP at 2 weeks (P = 0.007). There was significantly less microleakage with iRoot SP than with MTA Fillapex (P = 0.025 at 2 weeks; P < 0.001 at 3 months). Leakage decreased significantly over time in all specimens, except in group 2 (P = 0.473). In conclusion, removal of the smear layer had no adverse effect on the sealing properties of calcium silicate-based sealers. In addition, the sealing ability of iRoot SP was superior to that of MTA Fillapex. (J Oral Sci 56, 215-219, 2014)

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Antibacterial activity of two MTA‐based root canal sealers

Abstract: MTA Fillapex and Endofill had an antibacterial effect against E. faecalis before setting, but none of the sealers maintained antibacterial activity after setting, despite the high pH of the MTA-based materials.

Cited by 116 publications

References 35 publications

Antimicrobial Activity of MTA Fillapex, Real Seal SE, Acroseal and Zinc oxide Eugenol Sealers against Enterococcus Faecalis and Candida Albicans

Antimicrobial Activity of MTA Fillapex, Real Seal SE, Acroseal and Zinc oxide Eugenol Sealers against Enterococcus Faecalis and Candida Albicans

Evaluation of the Physicochemical Properties and Push- Out Bond Strength of Mta-based Root Canal Cement

Effect of the smear layer on apical seals produced by two calcium silicate-based endodontic sealers

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