Antibacterial and antifungal activity of Senecio inaequidens DC. and Senecio vulgaris L.

Loizzo, Monica Rosa; Statti, Giancarlo; Tundis, Rosa; Conforti, Filomena; Bonesi, Marco; Autelitano, G; Houghton, Peter J.; Miljkovic-Brake, Ana; Menichini, Francesco

doi:10.1002/ptr.1562

Cited by 43 publications

(37 citation statements)

References 6 publications

(6 reference statements)

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“…Loizzo et al (2006) indicated that the n-hexane extract of S. samnitum displayed the best antibacterial activity against Gram + bacteria, particularly S. aureus, and the different solvent extracts of this species had antifungal activities, particularly against the dermatophytes Trichophyton tonsurans and Microsporum gypseum for the methanol and n-hexane extracts. Same researchers have shown that the methanol extract of S. vulgaris exhibited antimicrobial activity against the Gram + bacteria while S. inaequidens had no antimicrobial activity against tested microorganisms and extracts of both Senecio species had no antimicrobial activities against Gram -bacteria and had weak activities against fungi (Loizzo et al, 2004). Pérez et al (1999) reported that essential oils of S. graveolens was active against Micrococcus luteus ATCC 9341, oxacillin-sensitive and oxacillin-resistant S. aureus, as well as antifungal effects on clinically isolated C. albicans.…”

Section: E Antimicrobial Activities Of the Senecio Speciesmentioning

confidence: 98%

“…There are many reports about antioxidant and antimicrobial properties of plants (Sagdic, 2003;Sagdic et al, 2006). Recent studies indicated that several species of Senecio exhibit antimicrobial, antifungal and cytotoxic activities (Barbetti et al, 1986;Pérez et al, 1999;Kiprono et al, 2000;El-Shazly et al, 2002;Garcia et al, 2003;Loizzo et al, 2004Loizzo et al, , 2006.…”

Section: Introductionmentioning

confidence: 99%

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Antimicrobial and antioxidant activities ofSeneciospecies growing in the Black Sea region, Turkey

Albayrak¹,

Aksoy²,

Hamzaoğlu

et al. 2008

Acta Botanica Gallica

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Abstract.-Total phenolic contents, antioxidant and antimicrobial activities of methanol extracts of six Senecio species growing in the Black Sea region of Turkey (S. pandurifolius, S. trapezuntinus, S. integrifolius subsp. aucheri, S. hypochionaeus var. argaeus, S. hypochionaeus var. ilkasiensis and S. lorentii) are investigated. The total phenolic content is analysed using Folin-Ciocalteu's reagent of the methanol extracts and varies from 19.54 to 81.78 mg GAE/g dry extract. The methanol extracts of the studied species possess antioxidant properties in the range of 70.07-165.21 mg AAE/g dry extract in phosphomolybdenum assay. S. hypochionaeus var. ilkasiensis extract shows maximum activity with an IC 50 of 15.94 µg/ml in DPPH free radical scavenging assay. All of the Senecio methanol extracts show similar antimicrobial activities against microorganisms tested by agar diffusion methods. Klebsiella pneumoniae is the most sensitive microorganism to the all extracts examined while Escherichia coli and Candida albicans are the most resistant one. Mots clés : activité antimicrobienne -activité antioxydante -DPPH -composés phénoliques -Senecio.

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Section: E Antimicrobial Activities Of the Senecio Speciesmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 99%

Antimicrobial and antioxidant activities ofSeneciospecies growing in the Black Sea region, Turkey

Albayrak¹,

Aksoy²,

Hamzaoğlu

et al. 2008

Acta Botanica Gallica

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“…(Detection limit = 0.1 ppb (EPA 2005). Studies have shown the importance of natural chemicals as a possible source of non-phytotoxic, systemic and easily biodegradable alternative fungicides (Loizzo et al, 2004). Mushin et al, 2001;Okigbo and Emoghene, 2003 reported that many plant extracts have been demonstrated to be effective in the control of several plant diseases as they exhibit a number of chemical and biological advantages as fungicides.…”

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confidence: 99%

Antifungal effect of Polar and non polar extracts of Aframomum Sceptrum on Two Isolates of Oil Palm

Okogbenin¹,

Emoghene²,

Okogbenin³

et al. 2014

Journal of Applied Sciences and Environmental Management

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ABSTRACT:In different parts of the world, attention is being paid to exploitation of higher plants as biodegradable fungicides in the control of most plant pathogenic fungi. Different spices of the Zingiberaceae family have been tested for their antifungal properties, but there exists little or no information on the antifungal potential of a particular member of that family; Aframomum sceptrum on fungal pathogens of some economic important palms in Nigeria. In this study, the phytochemical composition of the seed extracts of this spice was analyzed by standard methods while the antifungal activities of polar and non polar extracts of the spice was tested on two major isolates affecting the Oil palm, Fusarium oxysporum f.sp elaeidis and Hypocrea lixii (IMI 501885) Cold extraction using Acetone, Ethanol, Hexane, Methanol, and Diethylether solvents were used in the seed extract preparation. The broad spectrum fungicide, Mancozeb (80% wettable powder) was used as the positive control while the negative control was Dimethyl sulphoxide. The Dimethyl sulphoxide was also used to reconstitute the solvent extracts by dissolving the extracts and fungicides in appropriate amount of 15 % (v/v) to obtain a concentration of 0.0624g/ml. The phytochemical screening revealed the presence of the following phytochemicals in different quantities; Alkaloids, Terpenoids, Anthraquinones, Flavonoids Tanins, Saponins. Results obtained showed that all the extracts had a significantly higher antifungal effect (p< 0.05) than the broad spectrum fungicide, Mancozeb at 2000ppm. Non polar hexane seed extract had the highest percentage inhibition of 60.26% on Hypocrea lixii (IMI 501885 while the Polar ethanolic extracts with a percentage inhibition of 52.73 % on Fusarium f.sp elaeidis. Amongst all the extracts used in this study, the seed extracts that gave a low percentage inhibition of 42.45% was the non -polar acetone seed extract on Fusarium oxysporum fsp. elaeidis and methanol extract on H .lixii with the least percentage inhibition of 42.31%. The implications of these findings are discussed. © JASEM http://dx.doi.org/10.4314/jasem.v18 i2.4

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“…Some compounds isolated from the genus Senecio and some crude extracts are known to possess significant antimicrobial activities, including antibacterial, antifungal, and antitubercular activities. [18][19][20][21] Senecio scandens BUCH.-HAM. locally known as "Qianliguang," is one of the most popular species used as a Chinese medicinal herb.…”

Section: Ninety-day Subchronic Oral Toxicity Study Of Senecio Scandenmentioning

confidence: 99%

Ninety-Day Subchronic Oral Toxicity Study of Senecio scandens Extract in Rats

Wang

Zhao

Liu

et al. 2015

Biological & Pharmaceutical Bulletin

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The present study assessed the safety/toxicity of Senecio scandens, a well-known Chinese herb that is used as an anti-inflammatory, antibiosis, and antipyretic drug. A 90-d subchronic oral toxicity study of S. scandens was performed in Wistar rats. The extract of S. scandens was administered orally to male and female rats at a single dose of 225, 450, and 900 mg/kg/d. There was no obvious toxicity. Certain changes in hematology and coagulation parameters (red cell distribution width (RDW), platelet count (PLT), monocyte percentage (Mo%), activated partial thromboplastin time (APTT), prothrombin time (PT)) were observed in some administration groups. In regards to the blood biochemical parameters, the levels of creatinine (CRN), potassium, and chloride were increased in a number of the treated rats. There were no significant changes in other hematology, coagulation, or biochemical parameters in rats orally administered S. scandens. S. scandens has a slight effect on rat coagulation and metabolism systems. The herb was safe at all doses tested, but caution should be taken when administering S. scandens at higher doses.

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Antibacterial and antifungal activity of Senecio inaequidens DC. and Senecio vulgaris L.

Cited by 43 publications

References 6 publications

Antimicrobial and antioxidant activities ofSeneciospecies growing in the Black Sea region, Turkey

Antimicrobial and antioxidant activities ofSeneciospecies growing in the Black Sea region, Turkey

Antifungal effect of Polar and non polar extracts of <i>Aframomum Sceptrum</i> on Two Isolates of Oil Palm

Ninety-Day Subchronic Oral Toxicity Study of <i>Senecio scandens</i> Extract in Rats

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