Antibacterial and Antioxidant Activity of Metabolites From Bioconverted Docosahexaenoic Acid Using Gut Bacteria

Kannan, Visali; Anandan, R.; Sudalaimani, Dinesh Kumar; Srinivasan, Shantkriti; Athiappan, Murugan

doi:10.21203/rs.3.rs-674393/v1

Cited by 4 publications

(1 citation statement)

References 6 publications

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“…Furthermore, a study made by using the bio-converted EPA and DHA omega-3 components displaying antibacterial activities against Gram-positive bacteria (Bacillus subtilis, Listeria monocytogenes, Staphylococcus aureus) and Gram-negative bacteria (Enterobacter aerogenes, Escherichia coli, Pseudomonas aeruginosa, Salmonella enteritidis, S. typhimurium) (Shin et al 2007;Kannan et al 2021). The growth inhibition by both bio-converted EPA and DHA was similar against Gram-positive bacteria, but the bio-converted extract of DHA was more effective than EPA against Gram-negative bacteria (Shin et al 2007).…”

Section: Bekele Et Al 2018)mentioning

confidence: 99%

The antimicrobial activity of vitamin D 3 and omega-3 combination against pathogenic microorganisms

Al-Najjar

Abdulrazzaq

Barakat

et al. 2023

Preprint

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Food supplemnts such as vitamin D3 and omega-3 have a significant impact on controlling pathogens. This study aims to evaluate the antimicrobial activities of combined vitamin D3 and omega-3 against selected pathogens. Minimum inhibitory activities of different serial dilutions of vitamin D3 (1.8 µM-216.6 µM) or omega-3 (0.8 mM-110 mM) or combined (vitamin D3: 0.8 µM -108.2 µM and omega-3: 0.3 mM -55 mM) have been investigated on Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Candida albicans. All the tested concentrations of vitamin D3 and omega-3 as a separate treatement were significantly different from the positive control in terms of microbial log-reduction. The highest concentration of vitamin D3 demonstrated a complete eradication of the tested microorganisms. Conversely, omega-3 had a lower effect on them. Combining 27 µM vitamin D3 and 13.5mM omega-3 resulted in ~ 0.4 to 0.6 log reduction of S. aureus, E.coli, P. aeuregnosa and C. albicans. On the other hand, C. albicans had 1.1 log reduction at a combination of 108.4 µM vitamin D3 and 55 mM of omega-3. Proposed mechanisms of the lowered antimicrobial activity when using the combination are discussed. These findings showed decreased antimicrobial effect of the combination and suggest a similar in vivo study to evaluate wheather taking the combination together or not.

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Section: Bekele Et Al 2018)mentioning

confidence: 99%

The antimicrobial activity of vitamin D 3 and omega-3 combination against pathogenic microorganisms

Al-Najjar

Abdulrazzaq

Barakat

et al. 2023

Preprint

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Research on the Effects of the Juncus Inflexus Subsp. Inflexus Extract on Low Dose Thioacetamide‐Induced Liver Damage: A Novel Antioxidant

Kaya,

KAYMAK,

Akin

et al. 2024

ChemistrySelect

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In this study was investigated the effects of extract of the Juncus inflexus subsp. inflexus (JI) plant on thioacetimide (TAA)‐induced liver damage. Six experimental groups were formed using 42 8–12‐weeks old Sprague dawley male rats, with seven experimental animals per group. Liver tissue sections were examined by staining with hematoxylin eosin (H‐E), periodic acid schiff (PAS) and caspase‐3. On the other hand, the tissue homogenates were analyzed by enzyme linked immunosorbent assay (ELISA), in terms of malondialdehyde (MDA) and glutathione (GSH). Compared to other groups, it was observed that the MDA rose significantly in the TAA group and that the GSH fell and that the expression of the caspase‐3 was significantly increased. On the other hand, it was found that lipid peroxidation decreased significantly in the TAA + JI group when compared to JI + TAA group. Also, to see the antioxidant properties of the plant in detail, molecular dynamic simulations were done. The antioxidant property of 59.16% in extract compounds of JI was theoretically demonstrated. The antioxidant activity of the 10‐methoxy‐nb‐alpha‐methylcorynantheol molecule, which is found at the highest rate in the relevant plant, has been theoretically revealed for the first time. In conclusion, this study has revealed that the extraction obtained from the Juncus inflexus plant has protective and therapeutic properties for the liver.

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Anti-foam cell activity of metabolites of a bacterium isolated from yogurt

Pramanik,

Sil

2024

Food Sci Biotechnol

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Antibacterial and Antioxidant Activity of Metabolites From Bioconverted Docosahexaenoic Acid Using Gut Bacteria

Cited by 4 publications

References 6 publications

The antimicrobial activity of vitamin D 3 and omega-3 combination against pathogenic microorganisms

The antimicrobial activity of vitamin D 3 and omega-3 combination against pathogenic microorganisms

Research on the Effects of the Juncus Inflexus Subsp. Inflexus Extract on Low Dose Thioacetamide‐Induced Liver Damage: A Novel Antioxidant

Anti-foam cell activity of metabolites of a bacterium isolated from yogurt

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