Antibacterial, antifungal and antioxidant activity of Cleome coluteoides: An In Vitro Comparative Study between Leaves, Stems, and Flowers

Moghaddam, Parastoo Zarghami; Mohammadi, Ameneh; Alesheikh, Paiman; Feyzi, Peyman; Haghbin, Ali; Mollazadeh, Samaneh; Sabeti, Zahra; Nakhlband, Ailar; Kasaian, Jamal

doi:10.4274/tjps.59320

Cited by 2 publications

(2 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The methanol extract of the leaf and the ethyl acetate extract of flowers had the highest antioxidant and antimicrobial activities, respectively, which are probably related to the total phenolics content. 37…”

Section: Discussionmentioning

confidence: 99%

Extraction, Isolation and Characterization by HPLC-ESI-MS and Evaluating Chemical Constituents of Hydroalcoholic Extracts of the Invasive Weed Cleome viscosa L.

Alamdari

Avarseji

Taleghani

2022

Natural Product Communications

View full text Add to dashboard Cite

The aim of this study was to extract, identify and isolate the chemical constituents of the root and leaves of Cleome viscosa by liquid chromatography coupled to electrospray ionization mass spectrometry (LC-ESI-MS). The antioxidant activity and content of associated secondary metabolites in the extracts from different parts of the plant were also measured. The free radical scavenging activity of the methanol extracts of different parts of C viscosa was determined using DPPH assays. A wide range of polar and non- polar compounds were characterized by LC-ESI-MS. Based on the obtained results, 22 and 21 compounds were characterized in the extracts of leaf and root of C viscosa, respectively. Among these compounds, cleomeolide and 57,4′.trihydroxy-6,3.5-trimethoxyflavone, in the leaf extract, and nevirapine and vincetoxicoside A, in the root extract, were considered as main compounds. Phytochemical analysis also showed that the content of bioactive compounds varied remarkably in the extract of different parts of C viscosa. The leaf ethanol extract contained higher amounts of secondary metabolites, namely total phenols and flavonoids. The antioxidant activity of the extracts was also dependent on the plant parts, which was significantly correlated with the content of bioactive compounds studied. A strong free radical scavenging activity was observed for the methanol extract of the leaf (50.3%), followed by the flower (35.2%). In general, this study confirmed a wide range of compounds in different parts of the invasive weed C viscosa, especially in the leaf, with a high free radical scavenging activity.

show abstract

Section: Discussionmentioning

confidence: 99%

Extraction, Isolation and Characterization by HPLC-ESI-MS and Evaluating Chemical Constituents of Hydroalcoholic Extracts of the Invasive Weed Cleome viscosa L.

Alamdari

Avarseji

Taleghani

2022

Natural Product Communications

View full text Add to dashboard Cite

show abstract

“…Furthermore, the study reported by Deventhiran et al (2017) and Jana and Biswas (2011) showed that C. viscosa is used to treat infection, and lactam nonanoic acid is isolated from its root exudates has inhibitory activity on fungi due to its allelopathic and antimicrobial properties. Besides, Moghaddam et al (2021) reported that C. coluteoides has antifungal activity against Fusarium solani and Candida albicans while Gowdra et al (2019) stated that C. isocandra is able to inhibit the mycelial growth and spore germination of Alternaria solani Sorauer.…”

Section: Introductionmentioning

confidence: 99%

Analysis of Metabolites from Purple Cleome Extract (Cleome rutidosperma Linn.) as Potential Organic Fungicides

Ikhwan¹,

Indratmi²,

Hasanah³

et al. 2021

SJA

View full text Add to dashboard Cite

One way to overcome these pathogens is to spray plant extract, e.g., purple cleome plant (spider or bee plant -Cleome rutidosperma Linn.) extracts as organic fungicides (Aliyu and Prasad, 2020). Purple Cleome plant extract has a chemical compound, thiogluco-Abstract | One disease that often attacks chili (Capsicum L.) is anthracnose caused by Colletotrichum capsici [(Syd.) E.J. Butler & Bisby]. In the field, C. capsici is controlled with a chemical fungicide that harms the environment. The purple Cleome plant (Spider plant -Cleome rutidosperma Linn.) can be extracted and function as an organic fungicide for environment-friendly control. This research aimed to examine the type and concentration of purple cleome extract metabolites and understand their effectiveness in inhibiting C. capsici. Purple cleome leaf is extracted with 1:1 w/v absolute methanol and concentrated with 1:1 v/v cold absolute methanol, and then the supernatant is purified using a centrifuge. The metabolic analysis was performed using Gas Chromatography-Mass Spectrometry (GC-MS) and comparing the data with the National Center for Biotechnology Information (NCBI) database to obtain specific metabolites. The inhibition test was done with one control (P0: chemical fungicide) and two-level of treatment, i.e., the concentration of purple Cleome extract (P1: 80 % and P2: 40 %), then ANOVA and HSD test were carried out to find out the best treatment. The purple Cleome leaf extract contained three metabolite compounds as organic fungicides, namely propanoic acid 4.12 %, phenol 8.38 %, and isopropyl myristate 15.86 %. The inhibition test confirmed that 80 % (P2) purple cleome extract could suppress C. capsici attack up to 16.67 %, significantly higher than chemical fungicide (24.4 %).

show abstract

Antibacterial, antifungal and antioxidant activity of Cleome coluteoides: An In Vitro Comparative Study between Leaves, Stems, and Flowers

Cited by 2 publications

References 23 publications

Extraction, Isolation and Characterization by HPLC-ESI-MS and Evaluating Chemical Constituents of Hydroalcoholic Extracts of the Invasive Weed Cleome viscosa L.

Extraction, Isolation and Characterization by HPLC-ESI-MS and Evaluating Chemical Constituents of Hydroalcoholic Extracts of the Invasive Weed Cleome viscosa L.

Analysis of Metabolites from Purple Cleome Extract (Cleome rutidosperma Linn.) as Potential Organic Fungicides

Contact Info

Product

Resources

About