Antibacterial, Antifungal, and Insecticidal Potentials ofOxalis corniculataand Its Isolated Compounds

Abstract

Oxalis corniculata is a common medicinal plant widely used against numerous infectious diseases. The agrochemical potential of methanolic extract, n-hexane, chloroform, ethyl acetate, and n-butanol fractions were assessed to measure the antibacterial, antifungal, and insecticidal activities of the plant. The crude, chloroform, and n-butanol soluble fractions showed excellent activities against Escherichia coli, Shigella dysenteriae, Salmonella typhi, and Bacillus subtilis but have no activity against Staphylococcus aureus. Similarly the crude, n-hexane, and chloroform fractions were also found to have significant activity against fungal strains including Fusarium solani, Aspergillus flexneri, and Aspergillus flavus and have no activity against Aspergillus niger. Chemical pesticides have shown very good results at the beginning, but with the passage of time the need was realized to use the natural plant sources for the safe control of insects. The current study will provide minor contribution towards it. High mortality rate was recorded for the crude extract and chloroform fraction against Tribolium castaneum. The two isolated compounds 5-hydroxy-6,7,8,4′-tetramethoxyflavone (1) and 5,7,4′-trihydroxy-6,8-dimethoxyflavone (2) were evaluated for antibacterial, antifungal, and insecticidal activities. The results showed that compound 2 was more active than compound 1 against the tested bacterial strains and insects.

Contributions to the phytotherapies of digestive disorders: Traditional knowledge and cultural drivers of Manoor Valley, Northern Pakistan

“…For the past about thirty two years, orally transmitted knowledge due to its economic value has been expanding and permitted the assemblage of such an important knowledge regarding medicinal plants actively investigated in less-developed areas such as Pakistan (Haq, 1983;Khan and Zaidi, 1991;Haq and Hussain, 1993;Bukhari, 1994;Hussain & Khalique, 1996;Shinwari and Khan, 2000;Gilani et al, 2001;Sher, 2002;Hamayun et al, 2003;Hussain, 2003;Hamayun, 2005;Gilani et al, 2006;Hamayun, 2007;Quraishi et al, 2008;Afzal et al, 2009;Ahmad et al, 2009;Qureshi et al, 2009;Abbasi et al, 2010a;Abbasi et al 2010b;Abbasi et al, 2010c;Hazrat et al, 2011;Shah et al, 2012;Abbasi et al, 2013;Akhter et al, 2013;Shah et al, 2013;Saqib et al, 2013;Ijaz, 2014;Ahmad et al, 2015;Butt et al, 2015;Ijaz et al, 2015;Kayani et al, 2015;Khattak et al, 2015;Ijaz et al, 2016). The traditional culture and the natural ecosystem of these regions have been relatively well conserved.…”

Extracts of Oxalis triangularis shows broad spectrum antibacterial activity in acidic condition

“…(Figure 1). It is interesting that the results differ from that of O. corniculata which the extracts of O. corniculata showed no antibacterial activity against S. aureus [21]. However, other report with methanolic extract of O. corniculata showed antimicrobial activity against S. aureus and various Shigella strains [22].…”

“…It is not excluded that other biologically active compounds in bactericidal activity rather than oxalic acid may be existed in the extracts of O. triangularis plants. The previous report revealed that the isolated antibacterial substances in the extracts of O. corniculata were 5-hydroxy-6, 7, 8, 4tetramethoxyflavone and 5, 7, 4'-trihydroxy-6, 8dimethoxyflavone [21]. It could be predicted that the concentration and pH effects by oxalic acid or oxalate salts would be affected to other biological activities such as antifungal or insecticidal effects [21].…”

Antibacterial and Antifungal Activities of the Medicinal Plant Veronica biloba

“…Agar welldiffusion method was used for antimicrobial screening using a standard protocol of clinical laboratory prescribed by national committee [31]. Extracted plant antibiotics are safe, effective, and have no or little side effects [32]. e active phytochemicals are responsible for biological activity such as antimicrobial against pathogens provide help in discovery of new antibiotic drugs [33][34][35].…”