“…It is commonly known as the hophead philippine violet and by various local names, such as Penawar seribu bisa (Malaysia) [ 8 ], Landik (Indonesia) [ 9 ], Sa-let-pangpon, Chong-ra-ar (Thailand) [ 10 ], Kanta vishalyakarni (India), and Neel saireyak (Sanskrit) [ 11 ]. Traditionally, B. lupulina was used to treat several diseases, including treating snake bites, dog bites, swelling, bleeding wounds, rheumatism, herpes simplex, and herpes zoster [ 10 , 11 ]. Studies have documented that B. lupulina has medicinal values, including anti-inflammation [ 12 ], antiviral [ 13 , 14 ], antibacterial [ 11 , 15 , 16 ], antidiabetic [ 17 ], cytotoxic [ 18 , 19 ], antidiuretic, and antiarthritic activity [ 20 , 21 ].…”