Antibacterial Effect of Visible Light Reactive TiO&lt;SUB&gt;2&lt;/SUB&gt;/Ag Nanocomposite Thin Film on the Orthodontic Appliances

Yun, Kwi-Dug; Oh, Gye-Jeong; Vang, Mong-Sook; Yang, Hong-So; Lim, Hyun-Pil; Koh, Jeong‐Tae; Jeong, Woon-Jo; Yoon, Dong‐Joo; Lee, Kyung-Ku; Lee, Kwang-Min; Park, Sang Won

doi:10.1166/jnn.2011.4874

Cited by 10 publications

(4 citation statements)

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“…They have become a high‐demand material for consumer products (Edwards‐Jones, ). AgNPs are widely used in medicine and health, food processing and other fields because of its excellent antibacterial properties, large specific surface area, small size, strong surface activity, strong catalytic performances and other characteristics (Vance et al, ; Yun et al, ). The widespread application of nanosilver in commodities has greatly increased the chance of human exposure to AgNPs, and its potential toxicity has gradually attracted widespread attention.…”

Section: Introductionmentioning

confidence: 99%

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Genotoxic effects of silver nanoparticles with/without coating in human liver HepG2 cells and in mice

Wang

et al. 2019

J of Applied Toxicology

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With the rapid expansion of human exposure to silver nanoparticles (AgNPs), the genotoxicity screening is critical to the biosafety evaluation of nanosilver. This study assessed DNA damage and chromosomal aberration in the human hepatoma cell line (HepG2) as well as the effects on the micronucleus of bone marrow in mice induced by 20 nm polyvinylpyrrolidone‐coated nanosilver (PVP‐AgNPs) and 20 nm bare nanosilver (AgNPs). Our results showed that the two types of AgNPs, in doses of 20‐160 μg/mL, could cause genetic toxicological changes on HepG2 cells. The DNA damage degree of HepG2 cells in 20 nm AgNPs was higher than that in 20 nm PVP‐AgNPs, while the 20 nm PVP‐AgNPs caused more serious chromosomal aberration than 20 nm AgNPs. Both kinds of AgNPs caused genetic toxicity in a dose‐dependent manner in HepG2 cells. In the micronucleus test on mouse bone marrow cells, in doses of 10, 50 and 250 mg/kg body weight administered orally for 28 days once a day, the two kinds of AgNPs have no obvious inhibitory effect on the mouse bone marrow cells, and the effect of chromosome aberration could be documented at the high dose of 250 mg/kg. These results suggest that AgNPs have genotoxic effects in HepG2 cells and limited effects on bone marrow in mice; both in vitro and in vivo tests could be of great importance on the evaluation of genotoxicity of nanosilver. These findings can provide useful toxicological information that can help to assess genetic toxicity of nanosilver in vitro and in vivo.

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Section: Introductionmentioning

confidence: 99%

“…and other characteristics (Vance et al, 2015;Yun et al, 2011). The widespread application of nanosilver in commodities has greatly increased the chance of human exposure to AgNPs, and its potential toxicity has gradually attracted widespread attention.…”

mentioning

confidence: 99%

Genotoxic effects of silver nanoparticles with/without coating in human liver HepG2 cells and in mice

Wang

et al. 2019

J of Applied Toxicology

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“…As a substitute for metal nanoparticles, metal oxide nanoparticles have also been widely used as an antimicrobial agent. Titanium dioxide is one of the most commonly used non-silver nanoparticles [64][65][66][67] . Its antibacterial action is photo dependent, consequently generates free radicals during photocatalytic reactions.…”

Section: Titanium Dioxide a Nanocomposite As Antibacterial Agentmentioning

confidence: 99%

Review on Recent Advancement of Therapeutic Interventions in Combating Multidrug Resistant Bacteria

Chakraborty¹,

Ranjana²,

Sumana³

et al. 2020

Int J Pharma Bio Sci

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“…Ophthalmologic polymers with antibacterial properties containing nanoparticles such as Ag, Au and Pt are also being actively studied. [7][8][9][10] In addition, we recently reported onnanomaterial-containing polymers that can block UV since nanomaterials such as ZnO and SiNc [silicon 2,3-naphthalocyanine bis(trihexylsilyloxide)] can absorb UV and infrared light. 11 Polymers in contact lenses are used for various purposes depending on the type and usage of the contact lens, but the materials must satisfy the basic optical requirements, * Author to whom correspondence should be addressed.…”

Section: Introductionmentioning

confidence: 99%

Effects of Ag/Pt Nanoparticles on the Physical Properties of Copolymers Containing 2-Fluoro-5-Methylanisole

Sung¹

2013

j. nanosci. nanotech.

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The ophthalmic materials must satisfy the optical requirements, physical and chemical stability and fulfill biological requirements, such as biocompatibility to be used in hydrogel ophthalmic lenses. Polymeric materials for hydrogel lenses were prepared by the copolymerization of HEMA, NVP, MMA, EGDMA and FMA in the presence of antibacterial Ag and Pt nanoparticles and also the effect of these copolymers containing nanoparticles on oxygen transmissibility was then investigated. The combination where AgNPs were added produced a light-yellowish colored transparent ophthalmic lens. The copolymers containing Ag and Pt nanoparticles did not have significant impact on the water content and refractive index of the hydrogel contact lens, but the Ag/Pt nanoparticles reduced oxygen permeability to a certain extent. Furthermore, the spectral transmittance significantly decreased. The additive, 2-fluoro-5-methylanisole, did not effect significantly on the physical properties of the polymer, but it was able to block UV light to a certain extent. The water content and oxygen permeability slightly increased as the amount of FMAs increased.

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Antibacterial Effect of Visible Light Reactive TiO<SUB>2</SUB>/Ag Nanocomposite Thin Film on the Orthodontic Appliances

Cited by 10 publications

References 0 publications

Genotoxic effects of silver nanoparticles with/without coating in human liver HepG2 cells and in mice

Genotoxic effects of silver nanoparticles with/without coating in human liver HepG2 cells and in mice

Review on Recent Advancement of Therapeutic Interventions in Combating Multidrug Resistant Bacteria

Effects of Ag/Pt Nanoparticles on the Physical Properties of Copolymers Containing 2-Fluoro-5-Methylanisole

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