Antibacterial Gold Nanoparticles-Biomass Assisted Synthesis and Characterization

Abstract

Xylose is a natural monosaccharide found in biomass such as straw, pecan shells, cottonseed hulls, and corncobs. Using this monosaccharide, we report the facile, green synthesis and characterization of stable xylose encapsulated gold nanoparticles (Xyl-GNPs) with potent antibacterial activity. Xyl-GNPs were synthesized using the reduction property of xylose in an aqueous solution containing choloraurate anions carried out at room temperature and atmospheric pressure. These nanoparticles were stable and near spherical in shape with an average diameter of 15 +/- 5 nm. Microbiological assay results showed the concentration dependent antibacterial activity of these particles against both Gram-negative (Escherichia coli) and Gram-positive (Staphylococcus epidermidis) bacteria. Thus the facile, environmentally friendly Xyl-GNPs have many potential applications in chemical and biomedical industries, particularly in the development of antibacterial agents in the field of biomedicine.

Novel Synthesis of Kanamycin Conjugated Gold Nanoparticles with Potent Antibacterial Activity

“…To visualize morphological changes in bacteria after inoculation with Kan-AuNPs, cross-sections of bacteria were prepared with the aid of ultra-microtome and observed under a TEM ( Badwaik et al, 2011 , 2013 ). One mililiter of bacterial culture was incubated at 37°C, 150 rpm, for 12 h in the presence of the MIC of Kan-AuNPs.…”

Exploring the Frontiers of Green Nanotechnology: Advancing Biomedicine, Herbonanoceuticals, Environment, and Sustainability

“…Xylose, a monosaccharide found in various natural sources such as grass, corn, walnuts, and cotton seeds, has been utilized to bind gold nanoparticles, which effectively act as antibacterial agents against gram-positive microorganisms (Badwaik et al, 2013).…”

Herbonanoceuticals: A New Step Towards Herbal Therapeutics

“…Nanoparticle conjugation makes the herbal extracts more effective. Anti-cancer, drug delivery, anti-microbial, anti-anemic, anti-arthritic, anti-diabetic, antioxidant properties of green nanoparticles have been established till date [32,88,89,[94][95][96] (Table 1).…”

“…Xylose, a monosaccharide found in straw, corncobs, pecan shells and cottonseed hulls was used to synthesize and cap gold nanoparticle with effective antibacterial activity against gram positive bacteria [89]. Gold nanoparticle synthesized using Cinnamomum zeylanicum leaf broth exhibited efficient antibacterial activity against gram negative Escherichia coli, gram positive Staphylococcus aureus, and antifungal activity against Aspergillus niger and Fusarium oxysporum [90].…”