Herbonanoceuticals: A New Step Towards Herbal Therapeutics

Gomes, Antony; Ghosh, Sourav; Sengupta, Jayeeta; Datta, P. K.; Gomes, Aparna

doi:10.4172/2167-0412.1000162

Cited by 11 publications

(5 citation statements)

References 103 publications

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“…aspects. 56 The various phytoconstituents owned by plants are known to exert remedial properties for different health complaints including neurological disorders.…”

Section: Discussionmentioning

confidence: 99%

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Chemical Profiling and Dose-Dependent Assessment of Fear Reducing and Memory-Enhancing Effects of Solanum virginianum in Rats

et al. 2021

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The current study was planned to investigate the pharmacological basis of Solanum virginianum extract (SV.CR) pertaining to anxiolytic, antidepressant and memory-enhancing effects in rats. The SV.CR was analyzed in-vitro for phytoconstituents, antioxidant potential and anticholinesterase activity. The rats treated in a dose-dependent manner (25, 50 and 100 mg/kg of SV.CR) were subjected to behavioral tests for anxiety, depression and memory judgment followed by biochemical studies. A notable dose-dependent anxiolytic potential of SV.CR was observed in elevated plus maze and open field tests (P < 0.05). The decreased immobility time of the treated rats in the forced swim test (P < 0.01) unveiled the plant’s potential to reduce depression. Moreover, SV.CR treatment also reversed scopolamine-impaired cognition (P < 0.05) in various deployed memory and learning tasks. Biochemical studies of brain homogenates of SV.CR treated animals demonstrated decreased anticholinesterase activity and lipid peroxidation levels whereas increased levels of superoxide dismutase and glutathione peroxidase (P < 0.05 vs scopolamine group) were noted. The scientific validation of the study supported the use of Solanum virginianum in reducing anxiety, depression and amnesia in experimental models. Phytoconstituents in SV.CR such as oleanolic acid and caffeic acid might have played a significant neuroprotective role via modulation of oxidative stress and neurochemical aspects.

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“…aspects. 56 The various phytoconstituents owned by plants are known to exert remedial properties for different health complaints including neurological disorders.…”

Section: Discussionmentioning

confidence: 99%

“… 29 People are showing more interest in natural remedies due to their immediate accessibility, safety profile and economic aspects. 56 The various phytoconstituents owned by plants are known to exert remedial properties for different health complaints including neurological disorders.…”

Section: Discussionmentioning

confidence: 99%

Chemical Profiling and Dose-Dependent Assessment of Fear Reducing and Memory-Enhancing Effects of Solanum virginianum in Rats

et al. 2021

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“…The use of herbal extracts in the synthesis of nanoparticles is a promising area of research with great potential for various applications. Amongst further positive effects, the resulting herbal formulations are supposed to be less toxic [ 25 ]. The toxicity of nanoparticles prepared using herbal extracts compared to those prepared using standard synthesis methods can vary depending on several factors, such as the composition of the herbal extract, the method used for synthesis and the type of nanoparticle.…”

Section: Jayakodi Et Al On Nano-herbformulations In Medicinementioning

confidence: 99%

Biomimetic Nanotechnology Vol. 3

Gebeshuber

2023

Biomimetics

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Biomimetic nanotechnology pertains to the fundamental elements of living systems and the translation of their properties into human applications. The underlying functionalities of biological materials, structures and processes are primarily rooted in the nanoscale domain, serving as a source of inspiration for materials science, medicine, physics, sensor technologies, smart materials science and other interdisciplinary fields. The Biomimetics Special Issues Biomimetic Nanotechnology Vols. 1–3 feature a collection of research and review articles contributed by experts in the field, delving into significant realms of biomimetic nanotechnology. This publication, Vol. 3, comprises four research articles and one review article, which offer valuable insights and inspiration for innovative approaches inspired by Nature’s living systems. The spectrum of the articles is wide and deep and ranges from genetics, traditional medicine, origami, fungi and quartz to green synthesis of nanoparticles.

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“…Tremendous applications of such nanomaterials based herbal preparations in the field of biomedicine have led to an innovative concept of ‗Herbo-nanoceuticals' (Gomes et al, 2014).…”

Section: Metal Nanoparticles Based Drug Deliverymentioning

confidence: 99%

Current Knowledge on Nanodelivery Systems and Their Beneficial Applications in Enhancing the Efficacy of Herbal Drugs

Ambwani¹,

Tandon²,

Ambwani³

et al. 2018

JEBAS

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Herbal remedies have been extensively used since times immemorial throughout the world. These have wide acceptability due to their time-tested therapeutic values and minimal side effects in contrast to modern allopathic medicines. Commonly, the herbal medicines are available in the form of crude extracts prepared in different solvent systems which might not only need large dose administration but also could be less effective in the form of conventional formulations. Moreover, available phytoformulations do not have the ability for specific tissue target delivery in case of different chronic diseases. Oral administration of these herbal formulations is subjected to adverse pH, enzymatic degradation and ultimately poor gut absorption and bioavailability. With the advancements in biotechnology, genomics, and combinatorial chemistry, new, more potent and specific drug delivery systems have been envisaged during the last few decades. Constraints associated with conventional phytopharmaceuticals have been improved by designing and using -Nano Delivery Systems‖ (NDS). The foremost aim of NDS is to provide sustained drug release, site-specific action, and improved patient's compliance. Nano herbal medicines can be used to target them to the specific site in the body which improves their selectivity, solubility, delivery, safety, effectiveness and thus reduces the need for

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Herbonanoceuticals: A New Step Towards Herbal Therapeutics

Cited by 11 publications

References 103 publications

Chemical Profiling and Dose-Dependent Assessment of Fear Reducing and Memory-Enhancing Effects of Solanum virginianum in Rats

Chemical Profiling and Dose-Dependent Assessment of Fear Reducing and Memory-Enhancing Effects of Solanum virginianum in Rats

Biomimetic Nanotechnology Vol. 3

Current Knowledge on Nanodelivery Systems and Their Beneficial Applications in Enhancing the Efficacy of Herbal Drugs

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