Antibacterial macro molecules from marine organisms

Nalini, S.; Richard, D. Sandy; Riyaz, S.U. Mohammed; Kavitha, G.; Inbakandan, D.

doi:10.1016/j.ijbiomac.2018.04.110

Cited by 46 publications

(30 citation statements)

References 72 publications

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“…Flavonoids as antibacterial have three ways of working, the first by inhibiting nucleic acid synthesis, the second is by inhibiting cytoplasmic membrane function and the third by inhibiting energy metabolism [29,30]. Phenol can inhibit bacteria by destroying the plasma membrane.…”

Section: Disc Diffusion Testmentioning

confidence: 99%

Potential of Dayak Onion (Eleutherine palmifolia (L) Merr) Extract As Antibacterial Against Pseudomonas fluorescens

Fransira

Yanuhar

Maftuch

2019

JELS

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Dayak onions (E. palmifolia (L) Merr) is a herb used as medicine and known to have antibacterial activity. This research aimed to evaluate antibacterial activity of Dayak onion (Eleutherine palmifolia (L) Merr) extract against fish pathogen Pseudomonas fluorescens. The method used in this study was extraction by maceration, UV-Vis spectrophotometry analysis on the extract and antibacterial activity test with Minimum Inhibitory Concentration (MIC) as well as disc diffusion test. The results of this study showed that the yield value was 8.87%. Based on UV-Vis analysis, it confirmed that extract of Dayak onion (Eleutherine palmifolia (L) Merr) contains predominantly flavonoids and phenols with its derivatives, that have antibacterial activity. The results of MIC and disc diffusion test showed potential antibacterial activity against P. fluorescens, as observed from the value of absorbance and inhibition zones that formed.

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Section: Disc Diffusion Testmentioning

confidence: 99%

Potential of Dayak Onion (Eleutherine palmifolia (L) Merr) Extract As Antibacterial Against Pseudomonas fluorescens

Fransira

Yanuhar

Maftuch

2019

JELS

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“…Thus, marine microorganisms appear to be a treasure trove of new active microbial drugs [8,9]. Recent studies have fully demonstrated that marine actinomycetes can produce a variety of secondary metabolites with diverse biological activities, including antibacterial [10,11], anti-tumor [12], anti-inflammatory [13], immune regulation [14], anti-parasitic [15], anti-oxidation [16], and anti-virus [17].…”

Section: Introductionmentioning

confidence: 99%

Shellmycin A–D, Novel Bioactive Tetrahydroanthra-γ-Pyrone Antibiotics from Marine Streptomyces sp. Shell-016

et al. 2020

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Four novel bioactive tetrahydroanthra-γ-pyrone compounds, shellmycin A–D (1–4), were isolated from the marine Streptomyces sp. shell-016 derived from a shell sediment sample collected from Binzhou Shell Dike Island and Wetland National Nature Reserve, China. The structures of these four compounds were established by interpretation of 1D and 2D NMR and HR-MS data, in which the absolute configuration of 1 was confirmed by single crystal X-ray diffraction, and compound 3 and 4 are a pair of stereoisomers. Compound 1–4 exhibited cytotoxic activity against five cancer cell lines with the IC50 value from 0.69 μM to 26.3 μM. Based on their structure–activity relationship, the putative biosynthetic pathways of these four compounds were also discussed.

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“…All of the bacteria and fungi were active against MDR S. aureus and E. coli (Trianto et al, 2019b). Thomas et al (2010) and Nalini et al (2018) reported various groups of secondary metabolites compounds of marine fungi with antibacterial activities. Other studies have successfully isolated antipathogenic bacterial compounds from marine fungi.…”

Section: Introductionmentioning

confidence: 99%

Antibacterial Activities of the Extracts of Sponge-Associated Fungus Trichoderma longibrachiatum against Pathogenic Bacteria

Sedjati

Ambariyanto

Trianto³

et al. 2020

Squalen Bull. Marine Fisheries Postharvest Biotech.

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This study aims to explore the antibacterial potential of a sponge-associated fungus Trichoderma longibrachiatum isolated from Ternate waters, North Maluku, Eastern Indonesia. Various culture media were used to stimulate the production of secondary metabolites in T. longibrachiatum. The isolate was cultured in various media for 6-9 days. Then, the antibacterial activities of the ethyl acetate extracts were assayed against pathogenic bacteria of Multi-Drug Resistant (MDR) strain (Pseudomonas aeruginosa, Staphylococcus aureus, Klebsiella pneumoniae, and Bacillus cereus). The results showed that all extracts had similar profiles on the thin layer chromatography. However, two of the most potent extracts were produced from the PCA and MEA media for 9 days. These extracts inhibited methicillin-resistant S. aureus (MRSA) (12.48 mm and 12.27 mm); B. cereus (12.11 mm and 12.12 mm); K. pneumoniae (12.40 mm and 10.76 mm); and P. aeruginosa (11.59 mm and 8.69 mm) at concentrations 500 mg/disc. In conclusion, the fungus T. longibrachiatum that was cultured in PCA and MEA media had the potential to produce antibacterial compounds against MDR pathogens and both had similar compounds. Meanwhile, the ethyl acetate extracts from fungus cultured in the TPA and TA media were inactive against all tested bacteria

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Antibacterial macro molecules from marine organisms

Cited by 46 publications

References 72 publications

Potential of Dayak Onion (Eleutherine palmifolia (L) Merr) Extract As Antibacterial Against Pseudomonas fluorescens

Potential of Dayak Onion (Eleutherine palmifolia (L) Merr) Extract As Antibacterial Against Pseudomonas fluorescens

Shellmycin A–D, Novel Bioactive Tetrahydroanthra-γ-Pyrone Antibiotics from Marine Streptomyces sp. Shell-016

Antibacterial Activities of the Extracts of Sponge-Associated Fungus Trichoderma longibrachiatum against Pathogenic Bacteria

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