2005
DOI: 10.1021/la0513306
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Antibacterial Properties of Ag Nanoparticle Loaded Multilayers and Formation of Magnetically Directed Antibacterial Microparticles

Abstract: Antibacterial coatings based on hydrogen-bonded multilayers containing in situ synthesized Ag nanoparticles were created on planar surfaces and on magnetic colloidal particles. We report the antibacterial properties of these coatings, determined using a disk-diffusion (Kirby-Bauer) test, as a function of the film thickness and the concentration of Ag nanoparticles in the hydrogen-bonded multilayers. The zone of inhibition (ZoI) determined by the disk-diffusion test increases as the thickness of the multilayer … Show more

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Cited by 452 publications
(355 citation statements)
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“…Although the competing mechanisms remain unclear, a large body of data suggests that both physical and chemical modifications of a material surface can be engineered to limit bacterial colonization. [5][6][7][8][9][10]12,13,20,22 For example, as shown in Figure 1, coating surgical-grade titanium alloy with a synthetic PEM of PAA and PAH reduced colony density of waterborne S. epidermidis bacteria by orders of magnitude after immersion in 10 7 bacteria/mL. Reduced colonization over both 2 and 4 h incubation timescales is relevant to medical procedure durations involving, for example, cardiac assist and orthopedic implant devices.…”
Section: Bacterial Colonization Can Be Reduced By Materialsmentioning
confidence: 99%
“…Although the competing mechanisms remain unclear, a large body of data suggests that both physical and chemical modifications of a material surface can be engineered to limit bacterial colonization. [5][6][7][8][9][10]12,13,20,22 For example, as shown in Figure 1, coating surgical-grade titanium alloy with a synthetic PEM of PAA and PAH reduced colony density of waterborne S. epidermidis bacteria by orders of magnitude after immersion in 10 7 bacteria/mL. Reduced colonization over both 2 and 4 h incubation timescales is relevant to medical procedure durations involving, for example, cardiac assist and orthopedic implant devices.…”
Section: Bacterial Colonization Can Be Reduced By Materialsmentioning
confidence: 99%
“…To prevent these problems, a large amount of research is carried out to develop preventive antimicrobial coatings on surfaces, including either antiadhesive or biocidal strategies. In the latter, one mainly finds either a killing-by-contact 5 or a killing-by-release 6 approach, where the active compound can be antibiotic 7 , quaternary ammonium derivatives 5 , nanoparticles 8 , etc., either blended into or deposited onto a substrate 9 , or chemically grafted onto surfaces. Nevertheless, the ecotoxicity of most of these compounds, the increasing resistance of microorganisms, or the complexity of the grafting strategy restrict their practical use at large scales.…”
Section: Introductionmentioning
confidence: 99%
“…Then, upon immersion in the salt solution, only the pressed regions are activated and promote NP growth therein, as illustrated by the examples of a fingerprint in Figure 5c and photolithographically defined patterns in Figure 5d. Third, when the tapes are decorated by Ag NPs, these particles confer their bacteriostatic and bacteriocidal effects 15,16 on the polymeric surfaces, as illustrated in Figure 5b. Fourth, deposition of the metallic NPs increases the tape's electrical conductivity, as illustrated in Figure 5e (4.81 × 10 −5 S/m for Au NP-decorated tape vs 1.15 × 10 −6 S/m for the native tape).…”
mentioning
confidence: 99%