2021
DOI: 10.1016/j.msec.2021.111895
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Antibacterial, thermal decomposition and in vitro time release studies of chloramphenicol from novel PLA and PVA nanofiber mats

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Cited by 25 publications
(9 citation statements)
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“…3 A). The HPMC nanofibers are hypoallergenic and have excellent biocompatibility and skin adhesion 24 , 25 , while PVA is an excellent matrix for storing and releasing drug molecules 26 , 27 . The two HPMC layers are 5.2 μm thick and consist of 110 ± 20 nm nanofibers to provide structural support for the 30.5 mm thick electrospun PVA (200 ± 40) nm.…”
Section: Resultsmentioning
confidence: 99%
“…3 A). The HPMC nanofibers are hypoallergenic and have excellent biocompatibility and skin adhesion 24 , 25 , while PVA is an excellent matrix for storing and releasing drug molecules 26 , 27 . The two HPMC layers are 5.2 μm thick and consist of 110 ± 20 nm nanofibers to provide structural support for the 30.5 mm thick electrospun PVA (200 ± 40) nm.…”
Section: Resultsmentioning
confidence: 99%
“…This compound is a broad-spectrum antibiotic isolated from the bacterium species, namely Streptomyces venezuelae (Roushani et al 2020 ). Based on binding to the bacterial ribosomal subunit, chloramphenicol inhibits the formation of protein, causing bacterial death (Bayrakci et al 2021 ). Thereby, chloramphenicol is preferable to the treatment of diseases regarding gram-positive, gram-negative, and anaerobic bacteria in humans and animals (Busch et al 2020 ).…”
Section: Introductionmentioning
confidence: 99%
“…[25][26][27] The commonly used methods for preparing nanofibers include centrifugal spinning, [28][29][30] electrospinning, [31][32][33] pressurized gyration, [34][35][36] self-assembly, [37][38][39] and chemical synthesis. [40][41][42] Among them, electrospinning and centrifugal spinning are the two most effective preparation methods.…”
Section: Introductionmentioning
confidence: 99%