Antibiofilm Activity of Ginger (Zingiber officinale) Extracts In Vitro and Food Model

Akbari, Saeed; Didar, Zohreh; Vazifedoost, Mohsen; Hajirostamloo, Bahareh; Mohtashami, Mahnaz

doi:10.1155/2023/5134332

Cited by 4 publications

(2 citation statements)

References 36 publications

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“…10 g of the dry powder of ginger was mixed with 100 ml of distill water with mixed by an electrical mixer for half an hour, then the mixture was filtered using layers of medical gauze and rounded 3000 cycles during 10 minutes in centrifuge, then filtered using filter paper to get rid of impurities. The extract dried in the oven at 40 °C and then kept in the refrigerator until use [9].…”

Section: Methodsmentioning

confidence: 99%

The Bio-physiological Impact of Different Concentrations of Ginger Aqueous Extract in Awassi Ewes

Alsaadi,

Abdulazeez,

Noaman

2025

Egyptian Journal of Veterinary Sciences

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HIS STUDY was conducted to prove the physiological impacts of different concentrations of aqueous extract of ginger on some biochemical traits in mature ewes to find the best concentration to investigate the changes that happened in the physiological parameters of the animal. The study investigated the impact of aqueous extraction of ginger tubers at concentrations of 200, 300, and 400 mg/kg of body weight and depended on these treatments for 20 ewes for two months. The gradual increase in the approved concentrations of the aqueous extract of ginger tubers has also led to a gradual significant increase (p≤0.05) in the approved biochemical parameters, such as a decrease in blood glucose, an increase in total protein levels and blood albumin concentration, and a decrease in the level of AST and ALT liver enzymes. The results of the current study proved that treating of adult ewes by aqueous extracts of ginger tubers in different concentrations showed gradual important improvement and stability in vital biophysiological traits.

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Section: Methodsmentioning

confidence: 99%

The Bio-physiological Impact of Different Concentrations of Ginger Aqueous Extract in Awassi Ewes

Alsaadi,

Abdulazeez,

Noaman

2025

Egyptian Journal of Veterinary Sciences

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“…Akbari [ 14 ] investigated the activity of antibiofilms against pathogenic bacteria through subcritical water and aqueous-ethanolic extracts of ginger in broth cultures and food model agents. The results showed that 50% ( v/v ) ginger subcritical water extract had the highest antibiofilm activity, similar to 0.5% peracetic acid (control).…”

Section: Antibacterial and Antioxidant Properties Of Natural Extractsmentioning

confidence: 99%

Natural Extracts and Their Applications in Polymer-Based Active Packaging: A Review

Li,

Sun,

Weng

2024

Polymers

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At a time when food safety awareness is increasing, attention is paid not only to food and additives but also to packaging materials. Most current food packaging is usually made of traditional petroleum-based polymeric materials, which are not biodegradable and have adverse effects on the environment and health. In this context, the development of new non-toxic and biodegradable materials for extending the best-before date of food is receiving increasing attention. In addition, additives in packaging materials may migrate outward, resulting in contact with food. For this reason, additives are also seen as a transition from synthetic additives to natural extracts. Active extracts from animals and plants having good antioxidant and antibacterial properties are also beneficial for human health. It is indisputable that active extracts are ideal substitutes for synthetic additives. Polymer packaging materials combined with active extracts not only maintain their original mechanical and optical properties and thermal stability but also endow polymers with new functions to extend the shelf life of food. This review paper provides an overview of this promising natural extract-containing polymer-based active packaging, with a focus on plant essential oils (containing phenolics, monoterpenes, terpene alcohols, terpene ketones, and aldehydes), pigments (procyanidins), vitamins (vitamin B), and peptides (nisin). In particular, this paper covers the research progress of such active extracts, in single or compound forms, combined with diverse polymers (mostly biopolymers) for food packaging applications with particular focus on the antioxidant and antibacterial properties of packaging materials.

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Effects of Globularia cordifolia on colon cancer cells: antioxidant activity, inflammatory cytokine analysis and molecular docking studies

Torunoglu,

Aytar,

Aydın

et al. 2024

J Sci Food Agric

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BACKGROUNDThe present study aimed to comprehensively evaluate the anticancer, anti‐inflammatory, and antioxidant properties of Globularia cordifolia L. samples. The plant material was collected and extracted using the maceration method. Antioxidant activities were assessed through DPPH (i.e. 2,2‐diphenyl‐1‐picrylhydrazyl) and iron chelation assays, whereas phenolic and flavonoid contents were measured using spectrophotometric methods. Gas chromatography‐mass spectrometry analysis was performed to identify biologically active compounds. The cytotoxic effect on colon cancer cells was evaluated using MTT [i.e. 2,3‐bis‐(2‐methoxy‐4‐nitro‐5‐sulfophenyl)‐2H‐tetrazolium‐5‐carboxanilide] assays, and inflammatory cytokine levels were measured through an enzyme‐linked immunosorbent assay. Molecular docking studies investigated the interactions of bioactive compounds with the 4UYA protein, and ADME (i.e. absorption, distribution, metabolism, excretion and toxicity) modeling predicted their toxicity.RESULTSThe study revealed that the extract exhibited strong antioxidant activity with a median 50% inhibitory concentration (IC50) value of 39.48 ± 2.15 μg mL−1 in the DPPH assay and an effective iron chelation capacity with an IC50 value of 4.28 ± 0.19 mg mL−1. The total phenolic content was 662.51 ± 20.95 mg gallic acid equivalents g−1, and the flavonoid content was 114.99 ± 0.51 mg quercetin equivalents g−1, demonstrating the extract's richness in phenolic and flavonoid compounds. Significant antiproliferative effects were observed in colon cancer cells at a dose of 250 μg mL−1. Inflammatory cytokine analysis indicated a reduction in pro‐inflammatory responses. Molecular docking studies showed strong binding affinities between the bioactive compounds and the 4UYA protein, suggesting the mechanisms of action.CONCLUSIONThe findings indicate that G. cordifolia extract exhibits strong antioxidant, anti‐inflammatory and antiproliferative properties, making it a promising biomolecular agent for colon cancer therapy. The high phenolic and flavonoid contents, combined with the bioactive compounds' interactions with key molecular targets, underscore its potential therapeutic applications. © 2024 Society of Chemical Industry.

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Antibiofilm Activity of Ginger (Zingiber officinale) Extracts In Vitro and Food Model

Cited by 4 publications

References 36 publications

The Bio-physiological Impact of Different Concentrations of Ginger Aqueous Extract in Awassi Ewes

The Bio-physiological Impact of Different Concentrations of Ginger Aqueous Extract in Awassi Ewes

Natural Extracts and Their Applications in Polymer-Based Active Packaging: A Review

Effects of Globularia cordifolia on colon cancer cells: antioxidant activity, inflammatory cytokine analysis and molecular docking studies

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