Antibiofilm Effect of Cerium Nitrate against Bacteria and Yeast

Azevedo, Manuela; Cobrado, Luís; A, Silva Dias; Ramalho, Patrícia A.; Pina-Vaz, Cidália; Ag, Rodrigues

doi:10.15226/sojmid.2013.00106

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2019

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“…Cerium is a rare-earth element of the lanthanide group and has antibacterial properties [11]. In particular, cerium nitrate [12,13] and cerium oxide [14,15] have been used as antibacterial reagents. The uptake of cerium ions into cytoplasm can inhibit cellular respiration, oxygen uptake, glucose metabolism, and disrupt the cell membrane [16,17].…”

Section: Introductionmentioning

confidence: 99%

Cytocompatible and Antibacterial Properties of Chitosan-Siloxane Hybrid Spheres

et al. 2019

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Microporous spheres in a hybrid system consisting of chitosan and γ-glycidoxypropyltrimethoxysilane (GPTMS) have advantages in a range of applications, e.g., as vehicles for cell transplantation and soft tissue defect filling materials, because of their excellent cytocompatibility with various cells. In this study, microporous chitosan-GPTMS spheres were prepared by dropping chitosan-GPTMS precursor sols, with or without a cerium chloride, into liquid nitrogen using a syringe pump. The droplets were then freeze dried to give the pores of size 10 to 50 μm. The cell culture tests showed that L929 fibroblast-like cells migrated into the micropores larger than 50 μm in diameter, whereas MG63 osteoblast-like cells proliferated well and covered the granule surfaces. The spheres with cerium chloride showed antibacterial properties against both gram-negative and gram-positive bacteria.

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