ANTIBIOTIC AND VITAMIN B ₁₂ PRODUCTION BY A STEROID OXIDIZING ACTINOMYCETE

METABOLISM OF PROGESTERONE BY CYLINDROCARPON RADICICOLA AND STREPTOMYCES LAVENDULAE

“…Stock cultures of both organisms were maintained on agar slants and in a lyophilized condition. The techniques used in preparation of inoculum for these experiments were described previously for C. radicicola by Fried and Thoma (1956a) and for actinomycetes by Perlman et al (1955), and Fried and Thoma (1956b). All of the flask fermentations herein described were incubated at 25 C on a rotary shaker (2-in displacement, 280 rpm) in 250-ml Erlenmeyer flasks containing 50 ml of media.…”