Antibiotic Prophylactics on Curettage for Preventing Pelvic Inflammatory Disease Events: Is It Necessary?

Herawati, Fauna; Rahem, Abdul; Handayani, Dwi; Yulia, Rika

doi:10.22159/ajpcr.2018.v11i11.27817

Cited by 2 publications

(4 citation statements)

References 15 publications

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“…There is sufficient data supporting the use of prophylactic antibiotics for induced surgical abortion [3], [11], [13], [39], [41]. However, data on prophylactic antibiotics in surgery for retained products of conception, are far more ambiguous [2], [20].…”

Section: Discussionmentioning

confidence: 99%

“…As for the type of antibiotics of choice for prophylaxis in miscarriage surgery, there is more consistency [14], [39]. Since infections after obstetrical surgical interventions are usually caused by endogenous flora or STD, the antibiotic prophylaxis should cover gram-negative, -positive and anaerobic agents.…”

Section: Discussionmentioning

confidence: 99%

“…As discussed above, both oral doxycycline and metronidazole have proven to be efficient in miscarriage surgery for induced abortion [14], [36], [39].…”

Section: Choice Of Antibioticsmentioning

confidence: 99%

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Usefulness of Antibiotic Prophylaxis in Miscarriage Surgery for Induced Abortion and Retained Products of Conception: a Narrative Review

Cloet

2022

JWHCI

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Background: Miscarriage surgery is one of the most performed surgeries worldwide. Prophylactic antibiotics aim to avoid postoperative pelvic infection. Its use and benefit are well-known in induced surgical abortion, but far more ambiguous for miscarriage surgery for retained products of conception. Objective: To investigate the usefulness of prophylactic antibiotics in miscarriage surgery for retained products of conception and induced abortion and evaluate the antibiotic regimen of preference. Material and Methods: A comprehensive electronic literature search was conducted using PubMed, MEDLINE and Google Scholar. There were no specific inclusion criteria concerning study design, publication year, language, or study population. Results: When evaluating the effectiveness of antibiotic prophylaxis for surgical intervention in induced abortion, 12 out of 19 studies showed a significant reduction on pelvic infection compared to the control group. There was no consensus regarding type and regimen of antibiotics. Five studies investigated prophylaxis in interventions for retained products of conception, of which 2 could show a significant effect. Conclusion: There is evidence that antibiotic prophylaxis reduces the risk of pelvic infection. Single dose preoperatively is favoured, for its effectiveness and patient compliance. Doxycycline and metronidazole are preferred, as for the type of antibiotics. There is limited evidence that antibiotic prophylaxis for surgical removal of retained products of conception or non-viable pregnancies might reduce the risk of pelvic infection.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Usefulness of Antibiotic Prophylaxis in Miscarriage Surgery for Induced Abortion and Retained Products of Conception: a Narrative Review

Cloet

2022

JWHCI

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“…Apart from its effectiveness, antibiotics also carry a microbial resistance risk. Unnecessary antibiotic prescription is the most common sign of inappropriate antibiotic use [23][24][25][26][27]. Antibiotics should not be carelessly prescribed for acute gastroenteritis since the misuse of antibiotics contributes to antibiotic resistance, one of which is Clostridium difficile infection.…”

Section: Discussionmentioning

confidence: 99%

The ANTIBIOTIC CONSUMPTION AT A PEDIATRIC WARD AT A PUBLIC HOSPITAL IN INDONESIA

Herawati

Upa

Yulia

et al. 2019

Asian J Pharm Clin Res

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Objective: The aims of the study are to describe how antibiotics were used in a pediatric ward and to observe how they were prescribed for infectious diarrheas of bacterial origin indication. Diarrhea or acute gastroenteritis is one of the most common infection diagnoses observed among the hospitalized children. Rehydration therapy is the key treatment for children with diarrhea. With the zinc supplement, the duration of the hospital stay can be reduced. Thus, the decision whether the local or regional health authorities need to provide an antibiotic treatment depends on the etiology of the disease, the patient’s nutritional history and immunological status, and eventually, the severity of the disease. Good anamneses and diagnoses are essential to decide whether antibiotic treatment is required. Methods: The observation in this study consists of two phases. The first-phase observation was taken from the diagnosis and the number of antibiotics used in 2016 retrospectively calculated from each of the patients’ medical records. Meanwhile, the second phase descriptive observation was prospectively drawn from the stool culture and the number of antibiotics prescribed to 21 inpatient diarrhea children between May 2017 and December 2017. The amount of antibiotic consumption was administered based on defined daily dose (DDD) and days of therapy (DOT). Results: In 2016, 56% (828/1476) of the patients received antibiotic prescriptions. On average, the DDD per 100 bed-days was 45.57. In the prospective study, six of 21 patients with diarrhea were prescribed antibiotics intravenously. The DOT was 3.5 days and the DDD for these patients was 12.10/100 bed-days. Conclusion: There was a high consumption rate of antibiotics which was not indicated in each patient’s etiology of diarrhea in the hospital during the period. Thus, the recommendation is to encourage health authorities to judiciously prescribe antibiotics according to the guidelines.

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Antibiotic Prophylactics on Curettage for Preventing Pelvic Inflammatory Disease Events: Is It Necessary?

Cited by 2 publications

References 15 publications

Usefulness of Antibiotic Prophylaxis in Miscarriage Surgery for Induced Abortion and Retained Products of Conception: a Narrative Review

Usefulness of Antibiotic Prophylaxis in Miscarriage Surgery for Induced Abortion and Retained Products of Conception: a Narrative Review

The ANTIBIOTIC CONSUMPTION AT A PEDIATRIC WARD AT A PUBLIC HOSPITAL IN INDONESIA

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