Antibiotic prophylaxis in urological surgery, a European viewpoint

Grabe, Magnus

doi:10.1016/j.ijantimicag.2011.09.008

Cited by 27 publications

(28 citation statements)

References 75 publications

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“…On the other hand, authors such as Grabe et al, have classified these procedures as clean surgeries (Class I) given the low infectious complication rates they found [10]. Hence, there has not been a consensus on the use of antibiotic prophylaxis in this surgery [11].…”

Section: Introductionmentioning

confidence: 99%

Smoking increases the risk of surgical site infection after hydrocelectomy in adults: a retrospective cohort study in Brazil

Costa

Medeiros

Salles

2018

J Infect Dev Ctries

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Introduction: Surgical site infection (SSI) following hydrocelectomy is relatively uncommon, but it is one of the main post-operative problems. We aimed to describe the prevalence of SSI following hydrocelectomy among adult patients, and to assess predisposing risk factors for infection. Methodology: This retrospective cohort study was carried out at a university hospital and included hydrocelectomies performed between January 2007 and December 2014. Diagnosis of SSI was performed according to the Center for Diseases Control (CDC) guidelines. Multivariable logistic regression analysis was used to identify independent risk factors. Results: A total of 196 patients were included in the analysis. Overall, 30 patients were diagnosed with SSI (15.3%) and of these, 63.3% (19/30) were classified as having superficial SSI, while 36.7% (11/30) had deep SSI. The main signs and symptoms of infection were the presence of surgical wound secretion (70%) and inflammatory superficial signs such as hyperemia, edema and pain (60%). Among the 53 patients presenting chronic smoking habits, 26.4% (14⁄53) developed SSI, which was associated with a higher risk for SSI (odds ratio [OR] = 2.84, 95% confidence interval [CI] = 1.27 to 6.35, p < 0.01) in the univariate analysis. In the adjusted multivariable analysis, smoking habits were also statistically associated with SSI after hydrocelectomy (odds ratio [OR] = 2.84, 95% confidence interval [CI] = 1.30 to 6.24, p = 0.01). No pre-, intra-, or post-operative variable analyzed showed an independent association to SSI following hydrocelectomy. Conclusions: Smoking was the only independent modifiable risk factor for SSI in the multivariate analysis.

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Section: Introductionmentioning

confidence: 99%

Smoking increases the risk of surgical site infection after hydrocelectomy in adults: a retrospective cohort study in Brazil

Costa

Medeiros

Salles

2018

J Infect Dev Ctries

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“…The literature describes successful outcomes in veterinary practice after clamp application times varying from less than 5 seconds to 60 seconds. Up to 70% of practitioners apply the clamp twice or more to each cord (6,7,10,12).…”

Section: Discussionmentioning

confidence: 99%

“…Bilateral spermatic cord blocks and midline scrotal skin infiltration were performed using a mixture of 10 mL lignocaine Lidocaine 1% and 10 mL bupivacaine Bupivacaine 0.5% (9). In accordance with the guidelines of the European Association of Urology, it is not our practice to administer routine peri-operative antibiotic prophylaxis for so called "clean operations" where the urinary tract is not opened (10). Group 2 patients underwent CAT (Figure-1).…”

Section: Methodsmentioning

confidence: 99%

Clamp ablation of the testes compared to bilateral orchiectomy as androgen deprivation therapy for advanced prostate cancer

Zarrabi

2011

Int. braz j urol.

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Purpose: Burdizzo clamp ablation of the testes (CAT) may provide an incisionless, cost-effective form of androgen deprivation therapy (ADT) in men with adenocarcinoma of the prostate (ACP) who find bilateral orchiectomy (BO) unacceptable or can not afford medical ADT. The aim of this study was to compare CAT with BO as primary ADT in men with ACP. Materials and Methods: Written, informed consent was obtained from men with locally advanced or metastatic ACP. Patients were prospectively randomized to BO (n = 9) or CAT (n = 10) under local anaesthesia, and were evaluated 3 and 7 days, 6 weeks and 3 months post-procedure. The protocol was approved by the local institutional ethics committee. Statistical analysis was performed using Student's, Mann-Whitney's and Fisher's tests. Results: Mean duration of the procedure was significantly longer for BO than CAT (16.9 vs. 10.9 minutes). Mean pain scores during and after the procedure did not differ significantly. Serum testosterone decreased significantly on days 3 and 7 after CAT, but increased at 6 weeks, and was significantly higher than after BO. Serum luteinizing hormone increased significantly from day 3 after BO and from day 7 after CAT. Serum prostate specific antigen decreased significantly after BO, but not after CAT. Minor complications were more common after BO (89%) than CAT (40%). In the 9 men who did not achieve castrate levels of testosterone after CAT, BO was performed. Conclusions: CAT was quicker to perform and had a lower complication rate, but was not as effective as BO in achieving castrate serum testosterone levels.

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“…Esta es solo una de las varias medidas que reducen la infección del sitio operatorio y se recomienda solo cuando el beneficio potencial excede el riesgo y los costos anticipados. En la cirugía prostática la evidencia indica que disminuye la incidencia de bacteriuria, bacteriemia e ITU (43,44).…”

Section: Factores De Riesgo Para Complicaciones Infecciosasunclassified

Complicaciones infecciosas después de prostatectomía abierta y resección transuretral de próstata en pacientes con hiperplasia prostática benigna

Caro-Zapata

Vásquez-Franco

Correa-Galeano

et al. 2018

iatreia

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Antibiotic prophylaxis in urological surgery, a European viewpoint

Cited by 27 publications

References 75 publications

Smoking increases the risk of surgical site infection after hydrocelectomy in adults: a retrospective cohort study in Brazil

Smoking increases the risk of surgical site infection after hydrocelectomy in adults: a retrospective cohort study in Brazil

Clamp ablation of the testes compared to bilateral orchiectomy as androgen deprivation therapy for advanced prostate cancer

Complicaciones infecciosas después de prostatectomía abierta y resección transuretral de próstata en pacientes con hiperplasia prostática benigna

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