Antibiotic resistance in agriculture: Perspectives on upcoming strategies to overcome upsurge in resistance

Mann, Avantika; Nehra, Kiran; Rana, J. S.; Dahiya, Twinkle

doi:10.1016/j.crmicr.2021.100030

Cited by 104 publications

(61 citation statements)

References 102 publications

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“…Antibiotic therapy exerts selective pressure on pathogens leading to the survival of resistant forms. This process is widespread due to the frequent use or overuse of antibiotics in husbandry [99] and has been shown to be accelerated in polluted soils and sediments [100].…”

Section: The Use Of Microorganisms and Substances With Qq Activity To...mentioning

confidence: 99%

Quorum-Sensing Inhibition by Gram-Positive Bacteria

et al. 2022

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The modern paradigm assumes that interspecies communication of microorganisms occurs through precise regulatory mechanisms. In particular, antagonism between bacteria or bacteria and fungi can be achieved by direct destruction of the targeted cells through the regulated production of antimicrobial metabolites or by controlling their adaptive mechanisms, such as the formation of biofilms. The quorum-quenching phenomenon provides such a countermeasure strategy. This review discusses quorum-sensing suppression by Gram-positive microorganisms, the underlying mechanisms of this process, and its molecular intermediates. The main focus will be on Gram-positive bacteria that have practical applications, such as starter cultures for food fermentation, probiotics, and other microorganisms of biotechnological importance. The possible evolutionary role of quorum-quenching mechanisms during the development of interspecies interactions of bacteria is also considered. In addition, the review provides possible practical applications for these mechanisms, such as the control of pathogens, improving the efficiency of probiotics, and plant protection.

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Section: The Use Of Microorganisms and Substances With Qq Activity To...mentioning

confidence: 99%

Quorum-Sensing Inhibition by Gram-Positive Bacteria

et al. 2022

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“…Since their discovery, antibiotics have been broadly used to treat infections in humans and veterinary medicine. Moreover, they have been used to treat animal infections and, as growth promoters, to enhance production performance in the agriculture sector [ 1 ]. However, after many years of intensive use of antibiotics in different fields of our life, antimicrobial resistance has become one of the most significant threats to the public health.…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial and Antibiotic Resistance from the Perspective of Polish Veterinary Students: An Inter-University Study

Sobierajski

Mazińska

Chajęcka‐Wierzchowska

et al. 2022

Antibiotics

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The phenomenon of antibiotic resistance is a global problem that affects the use of antibiotics by humans and animal husbandry. One of the primary reasons for the growing phenomenon of antibiotic resistance is the over-prescription of antibiotics by doctors in human medicine and the overuse of antibiotics in industrial animal farming. Adequate education of veterinary medical students on the use of antibiotics in animal husbandry may reduce antibiotic resistance. For this reason, a survey was conducted among students at four primary research and didactic centers teaching veterinary medicine in Poland. The survey aimed to find out the knowledge and attitude of students towards the use of antibiotics and antibiotic resistance. The survey was conducted in May/June 2021. Four hundred and sixty-seven students participated in the study. The study positively verified that antibiotics and antibiotic resistance knowledge increase with successive years of veterinary studies/education. For most students (82.2%), antibiotic resistance is a significant problem, but only 58.7% believe it is global, and one in three respondents heard about the One Health approach.

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“…Antibiotics are crucial for fighting infectious diseases caused by bacteria. In animal production, antibiotics are used frequently to prevent and treat disease and were formerly used for growth promotion (Allen et al., 2010; Landers et al., 2012; Lima et al., 2020; Mann et al., 2021; Zaman et al., 2017). Chicken and turkey production in the United States uses significant amounts of antibiotics, representing 14% of medically important antibiotic use in animal agriculture in 2020 (FDA, 2020).…”

Section: Introductionmentioning

confidence: 99%

Prairie strips’ effect on transport of antimicrobial resistance indicators in poultry litter

et al. 2022

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Poultry litter is a valuable nutrient resource for agricultural production but is also a potential source for introducing antibiotic resistance genes (ARGs) and litter‐associated bacteria (LAB) to the environment. Prairie strips have been demonstrated as an effective conservation practice to improve environmental quality in agroecosystems. This research aims to assess prairie strips’ potential for reducing the transport of LAB and ARGs in runoff after litter application. Plot‐scale rainfall simulations were performed using a replicated block design, with soil and surface runoff samples taken during the rainfall event. Microbial taxa and ARGs were characterized in the litter, soil, and water samples. In plots with litter application, LAB and ARGs were mainly detected in runoff, with very low detection in soils. Detection of ARGs in runoff, irrespective of strip installations, is consistent with previous observations of litter as a source of antimicrobial resistance (AMR) risks. The effectiveness of prairie strips to remove LAB and ARGs varied. In two of the three prairie strip plots, fewer AMR indicators were detected relative to control plots, suggesting that the prairie strips can potentially reduce these risks. In one plot, which was also associated with increased flow rate, we observed increased AMR indicators despite the installation of a prairie strip. Our observations highlight the need to prioritize understanding of soil properties even within the same site. Although we show that prairie strips can potentially reduce AMR risks, further research is needed to better understand the influence of rainfall timing, soil, and litter characteristics.

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Antibiotic resistance in agriculture: Perspectives on upcoming strategies to overcome upsurge in resistance

Cited by 104 publications

References 102 publications

Quorum-Sensing Inhibition by Gram-Positive Bacteria

Quorum-Sensing Inhibition by Gram-Positive Bacteria

Antimicrobial and Antibiotic Resistance from the Perspective of Polish Veterinary Students: An Inter-University Study

Prairie strips’ effect on transport of antimicrobial resistance indicators in poultry litter

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