Antibiotic Resistance of Pathogens of Cervical Lymphadenitis in Guinea Pig in Peru

Abstract

The guinea pig (Cavia porcellus) is a small animal that provides a source of protein for the feeding of rural inhabitants of Peru. The frequency of pathogens associated with cervical lymphadenitis includes mainly pyogenic bacteria’s Streptococcus sp., Staphylococcus sp. and Corynebacterium sp. The spread of these pathogens can be controlled by applying biosecurity with thorough disinfection and rest of ponds or cages. In this context, antibiotic resistance is a growing problem in veterinary and human medicine, disfavoring antibiotic therapeutic efficacy that can nullify the curative action during treatment. We describe the main bacteria isolated from cervical lymphadenitis can be very sensitive to bacitracin, polymyxin, vancomycin and gentamicin. Which will allow the proper use of antibiotics in guinea pigs, as well as an efficient control focused in One World One Health. Antimicrobial resistance against lymphadenitis in guinea pigs in vivo has not been well studied in the regions of Peru. Resistance to enrofloxacin, penicillin and oxytetracycline, the most widely used antibiotics by producers, is suspected without considering the specificity or the spectrum of their pharmacological action; which could represent a relevant public health problem at the regional level. For these considerations we suggest carrying out resistance tests with animals previously administered with fluoroquinolones and the new beta-lactams.

Antibacterial activity of plant extracts against Streptococcus equi subsp. zooepidemicus isolates from guinea pigs with lymphadenitis in Ecuador

“…The guinea pig ( Cavia porcellus ) belongs to this family, is a mammal rodent native to the Andean region of Ecuador, Peru, Colombia, and Bolivia, domesticated 2500 to 3500 years ago [ 1 ]. It is crucial to produce meat with high nutritional value [ 2 ].…”

“…The guinea pig is a species of zootechnical interest that is attacked by infectious and parasitic diseases, which are associated with sudden changes in temperature, humidity, air currents, dirty pools, and changes in their diet [ 3 ]. These diseases are caused by bacteria, viruses, and fungi that cause the death of the animals [ 2 ]. Among the most frequent diseases are respiratory diseases (frequently caused by Bordetella , Streptococcus , and adenovirus), salmonellosis, chlamydiosis, pneumonia, and lymphadenitis [ 1 , 4 , 5 ].…”

“…The most common conditions are respiratory and gastrointestinal [ 1 , 4 ]. The pathogens associated with lymphadenitis frequently include pyogenic bacteria Streptococcus sp., Staphylococcus sp., and Corynebacterium sp [ 2 , 5 , 9 ].…”

“…The most commonly used antibiotics by guinea pig producers to treat lymphadenitis are enrofloxacin, penicillin, and oxytetracycline [ 2 ]. Including antibiotics as a mechanism to cure infectious diseases led to a significant medical breakthrough, making them a fundamental tool in science that has significantly improved animal health.…”