Antibiotic susceptibility of common bacterial pathogens in urinary tract infections in a Teaching hospital in Southwestern Nigeria

Oluremi, B. B.

doi:10.5897/ajmr11.405

Cited by 31 publications

(40 citation statements)

References 21 publications

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“…This may be as a result of increased sexual activity within this age group which predisposes them to UTI. This observation is supported by reports of other workers [40] [50] who found same.…”

Section: Discussionsupporting

confidence: 83%

“…This observation however indicates that the organism is also gaining clinical prominence in the etiology of UTI (Figure 1) and it is not in agreement with the much higher incidence rates recorded by other authors [1] [38] [40]- [44] in similar UTI investigations.…”

Section: Discussioncontrasting

confidence: 50%

“…[64], in contrast found Klebsiella species to be highly resistant to gentamycin and cephalexin. The high prevalence of multiple antibiotic resistant strains is a possible indication that very large populations of bacterial isolates have been exposed to several antibiotics [40].…”

Section: Discussionmentioning

confidence: 99%

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Incidence of Urinary Tract Infections (UTI) amongst Patients Attending Primary Health Centres in Anambra State

Ogbukagu¹,

Anakwenze²,

Ekwealor³

et al. 2016

AiM

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Urinary tract infections (UTIs) are one of the most prevalent extra-intestinal bacterial infections. It is a common disease encountered in medical practice affecting people of all ages, from neonate to geriatric age group. These infections are on the increase for outpatients attending Primary Health Centres in Anambra State, Nigeria, therefore the need for this study. The prevalence rate of urinary tract infection, age distribution and influence of sex were determined. Susceptibility pattern of the infectious organisms to antimicrobial agent were examined. Clean-catch midstream urine samples were collected and examined. Out of 3000 urine samples examined, 528 bacterial isolates were recovered and characterized. These include: Escherichia coli (24.2%), Klebsiella spp. (18.2%), Staphylococcus aureus (18.2%), Proteus mirabilis (9.1%), Pseudomonas aeruginosa (9.1%), Enterococcus faecalis (9.1%), Citrobacter intermedius (6.1%) and Staphylococcus saprophyticus (6.1%). More females (52%) were infected than males (48%) and in both sexes, the highest incidence was found amongst the age group, 26 -38 years. Gram negative rods had the highest incidence in both sexes. Among the towns in Anambra state, Umunya in southern province was observed to have the highest incidence rate of UTI. Susceptibility test of the bacterial isolates to antimicrobial agents showed that Staphylococcus aureus was sensitive to Cephalexin, Penicillin V, Erythromycin and Gentamycin while Pseudomonas aeruginosa was resistant to all the antibiotics. Escherichia coli and Klebsiella spp. were resistant to all the antibiotics except Gentamycin while Citrobacter intermedius was resistant only to Cephalexin and Erythromycin. This study provides the evidence of urinary tract infections amongst outpatients of primary health centres and the drugs for their control.

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Section: Discussionsupporting

confidence: 83%

Section: Discussioncontrasting

confidence: 50%

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Incidence of Urinary Tract Infections (UTI) amongst Patients Attending Primary Health Centres in Anambra State

Ogbukagu¹,

Anakwenze²,

Ekwealor³

et al. 2016

AiM

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“…Similar work was done by Olerumi et al [16] observed that the Ciprofl oxacin and Ofl axin could inhibit the growth of gram-negative bacteria. The extraction of crude extracts from Solanum nigrum (L.), Murraya koenigii (L.) and Sesbania grandifl ora (L.) from two different seasons by acetone was performed to detect the secondary metabolites.…”

Section: Minimal Inhibitory Concentration (Mic)supporting

confidence: 65%

Evaluation of Preliminary Phytochemical Constituents and Antibacterial Activity of Edible Plants against Urinary Tract Infection Causing Bacteria in Children

Arun¹

2017

J Clin Microbiol Biochem Technol

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The present study is aimed to determine the preliminary phytochemical screening and antibacterial activity of acetone extract of the edible plants, Solanum nigrum (L.), Murraya koenigii (L.), Sesbania grandiflora (L.) against urinary tract infection causing bacteria in children. These edible plant extracts were checked for their antibacterial activity by the agar disc diffusion method. The preliminary phytochemical screening of this extract revealed the presence of alkaloids, proteins, amino acids, anthraquinone glycosides, fl avonoids, tannins, phenolic compounds, carbohydrates, saponins and steroids. In the Kirby-Bauer disc diffusion method, Ciprofl oxacin showed the high zone formation against all the isolated bacterial strains. Among all the extracts, Murraya koenigii (L.) from winter season showed maximum inhibitory activity for all the isolated bacterial strains. The minimal inhibitory concentration values of the acetone extract of these three edible plants from two different seasons against the isolated bacterial strains were observed. The acetone extracts of these edible plants have a broad spectrum of antibacterial activity and support the traditional use of these plants as medicines.

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“…Samples with colony count equal or more than 10 5 Cfu/ml were considered positive. The isolates were identified and confirmed using standard microbiological methods including Gram staining, colonial morphology on media, growth on selective media, lactose and mannitol fermentation, H 2 S production, catalase, oxidase, coagulase, indole, and citrate utilization, and urease test (16)(17)(18).…”

mentioning

confidence: 99%

Antibiotic Susceptibility of Bacterial Strains Isolated From Urinary Tract Infections in Karaj, Iran

Khoshbakht

Salimi

Aski

et al. 2012

Jundishapur J Microbiol

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The article will help Clinicians in predicting and planning correct strategies for UTI therapy.Backgrounds: Urinary Tract Infection (UTI) is one of the most common bacterial diseases worldwidethat can be presented asymptomatic or symptomatic, characterized by a wide range of symptoms from mild irritative voiding to bacteremia, sepsis, or even death. In latter decades, widespread utilization of antibiotics has resulted in increased incidence of antibiotic resistance among urinary tract pathogens all over the world. Objectives: The aim of this study was to determine patterns of antibiotic resistance bacteria isolated from urinary tract infections in the city of Karaj, Iran. Materials and Methods: This descriptive study was conducted in the city of Karaj from November 2009 to August 2010. Bacterial isolates were identified by standard biochemical tests. Antibacterial susceptibility test was performed by Kirby-Bauer method against some common antibiotics for Gram negative and Gram positive bacteria and the data were analyzed by SPSS software, version 12.0.1. Results: In this study, 230 (8.06%)out of 2852 patients showed positive urine cultures of which there were 204 (88.69%) females and 26 (11.3%) males. 180 (83.17%) cases of isolated bacteria were Gram negative bacilli while 50 (21.73%) cases were Gram positive cocci. E. coli isolates, as the most frequent Gram negative bacteria, showed high resistance to cephalothin (88.16%) and high susceptibility to nitrofurantoin (90.78%). Also Staphylococcus saprophyticus isolates, as the most frequent Gram positive bacteria, exhibited high resistance to ampicillin, tetracycline, and erythromycin (92.31%) and high susceptibility to nitrofurantoin and vancomycin (92.3%). Conclusions: considering the results of this study, E.coli isolates were the predominant pathogens in UTI. Our data demonstrated that antibiotics with the highest activity included ciprofloxacin and nitrofurantoin and those with the least activity included ampicillin and sulfamethoxazole-trimethoprim. Our findings reinforce the need for ongoing investigations to show the trends of antibiotic resistance which can help antibiotic prescription in the clinics.

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Antibiotic susceptibility of common bacterial pathogens in urinary tract infections in a Teaching hospital in Southwestern Nigeria

Cited by 31 publications

References 21 publications

Incidence of Urinary Tract Infections (UTI) amongst Patients Attending Primary Health Centres in Anambra State

Incidence of Urinary Tract Infections (UTI) amongst Patients Attending Primary Health Centres in Anambra State

Evaluation of Preliminary Phytochemical Constituents and Antibacterial Activity of Edible Plants against Urinary Tract Infection Causing Bacteria in Children

Antibiotic Susceptibility of Bacterial Strains Isolated From Urinary Tract Infections in Karaj, Iran

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