Antibiotics After Preterm Premature Rupture of the Membranes

Singh, Katherine; Mercer, Brian M.

doi:10.1097/grf.0b013e318217ec5d

Cited by 16 publications

(21 citation statements)

References 15 publications

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“…1 Ascending choriodecidual infection appears to play an important role in etiology of PPROM. 2 Choriodecidual infection can be diagnosed by processing of amniotic fluid. However, because of invasive nature of procedure, need of expertise and difficulty in cultivating specific organisms, amniocentesis is not routinely done in low-resource settings.…”

Section: Introductionmentioning

confidence: 99%

Vaginal flora in preterm premature rupture of membranes and their sensitivity to commonly used antibiotics

Rani

Mehra

Gupta³

et al. 2014

Asian J Med Sci

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Background: Ascending infection is one of the most common etiologies in preterm premature rupture of membranes (PPROM). Antibiotics are used in PPROM to prolong the pregnancy and to prevent infection. But to prevent drug overuse and resistance, microorganism directed antibiotics should be used. So, this study was planned to evaluate vaginal flora in pregnant women with PPROM and their sensitivity to commonly used antibiotics. Methods: In this prospective cross-sectional study, 50 pregnant women (cases) preterm premature rupture of membranes and 28 pregnant women (controls) without complication were assessed for the type of vaginal flora and its sensitivity to commonly used antibiotics. Results: Among cases 18 (36%) women showed bacteria on Gram's staining of vaginal swabs with Gram-negative bacteria (10/18) being the most common. Among controls, 16 (57%) women showed bacteria on Gram's staining with Gram-positive bacteria being most common. Among cases Escherichia coli and Staphylococcus aureus were the commonest isolates. Of 8 (16%) positive bacterial cultures in cases, 6 (10%) were sensitive to Gentamicin and 2 (4%) to Ampicillin. Conclusion: Lower genital tract flora of pregnant women with PPROM predominantly consists of Gram-negative bacteria, which are sensitive to Gentamicin.

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Section: Introductionmentioning

confidence: 99%

Vaginal flora in preterm premature rupture of membranes and their sensitivity to commonly used antibiotics

Rani

Mehra

Gupta³

et al. 2014

Asian J Med Sci

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“…8,9 Although the most obvious intent of antibiotic therapy is to prevent infectious morbidity, it has also been proven efficacious in reducing many other complications of PPROM. However, polymicrobial infection likely plays a large role.…”

Section: General Managementmentioning

confidence: 99%

Preterm Premature Rupture of Membranes

&NA;

2013

Postgraduate Obstetrics & Gynecology

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“…[3] One of the most important contributing factors of PPROM is the presence of choriodecidual infection. [4] In the case of a pregnant woman becoming infected, microorganisms begin to attack the chorionic tissues and are excreted endotoxins and exotoxins. Thus, the chorionic tissues begin to secrete cytokine as an automatic reaction.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of maternal and neonatal outcomes in the case of preterm premature rupture of membranes and their relationship to prenatal maternal indicators: Across -sectional descriptive study

El-Kashif

Fathy²,

Elsaba³

2020

JNEP

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Background and aim: Preterm premature rupture of membranes is one of the most important causes of pregnancy complication and a significant role in the occurrence of perinatal morbidity and mortality. The present study aims to evaluate the maternal and neonatal outcomes in the case of preterm premature rupture of membranes and their relationship to prenatal maternal indicators. Subjects and methods: A cross-sectional descriptive design was used to evaluate 68 pregnant women with a gestational age of 32 to before 37 weeks, and singleton pregnancy complicated by preterm premature rupture of membranes who fulfilled the inclusion criteria. The data were collected by convenience sampling using standardized tools. Results: A linear correlation was used to show a correlation between maternal clinical indicators with the predictive maternal and neonatal outcome using a Spearman Rho correlation coefficient. The most significant neonatal outcomes are neonatal intensive care unit admission, neonatal respiratory distress syndrome, and early neonatal sepsis. More than two-thirds of the studied women had expectant management, and less than one-fourth of them have postnatal sepsis. Conclusion and recommendation: The prenatal maternal indicators are the significant values for maternal and neonatal outcome in case of preterm premature rupture of membranes, so A further larger prospective study is recommended to demonstrate the difference in incidence, management protocol of preterm premature rupture of the membranes in the delivery and maternity health care services.

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Antibiotics After Preterm Premature Rupture of the Membranes

Cited by 16 publications

References 15 publications

Vaginal flora in preterm premature rupture of membranes and their sensitivity to commonly used antibiotics

Vaginal flora in preterm premature rupture of membranes and their sensitivity to commonly used antibiotics

Preterm Premature Rupture of Membranes

Evaluation of maternal and neonatal outcomes in the case of preterm premature rupture of membranes and their relationship to prenatal maternal indicators: Across -sectional descriptive study

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