Antibodies, enzymes, and nucleic acid sensors for high throughput screening of microbes and toxins in food

Lateral flow based immunobiosensors for detection of food contaminants

“…Detection of these contaminants is of supreme importance to guarantee the quality of food. Biochemical characterization and microbiological identification are used as conventional methods for bacteria detection (Byrne, Gilmartin et al 2015). With the emphasis on fast bacterial pathogen detection, lateral flow test has been confirmed to be a rapid and sensitive method for the detection of food-borne pathogens (Keiser and Utzinger 2005;Law, Ab Mutalib et al 2015;Tallent, Hait et al 2015;Wang, Katani et al 2016).…”

“…Identification of antibodies against various pathogens is also the other advantageous that could be achieved by lateral flow test in serodiagnostic analysis (Dzantiev et al 4 4 2014). Besides, the development of lateral flow systems for food safety and quality control is a relatively new field of research which is under investigation by different researchers (Byrne, Gilmartin et al 2015;Cox, Jensen et al 2015;Xing, Liu et al 2015;Chen, Chen et al 2016;Song, Liu et al 2016). Many test kits have been recently developed for checking the presence of food allergen residues which have become commercially available.…”

Application of Biosensors in Diagnosis of Human Parvoviruses

“…The specificity of a biosensor for target analytes determines its success. For analyte detection, a biosensor for viral infection diagnosis requires the effective immobilization of antibodies, aptamers, nucleic acids, or peptides on the surface of a transducer (Figure I) 23 . The transducer can convert biological signals into electrical or optical signals.…”