Antibodies to Adenovirus in Patients With Infectious Hepatitis

Abnormal liver function in children hospitalized with acute respiratory infection of adenoviruses: a retrospective study

“…HAdVs cause acute hepatitis and liver failure in immunocompromised patients ( Onda et al., 2021 ), and few cases have been reported in immunocompetent patients ( Matoq and Salahuddin, 2016 ; Khalifa et al., 2022 ). Several early studies suggested the involvement of adenoviruses, directly or indirectly, in the etiology of infectious hepatitis ( Alwen, 1973 ; Munoz et al., 1998 ; Peled et al., 2004 ; Ozbay Hosnut et al., 2008 ). However, it remains unclear whether HAdVs are a definite contributor to hepatitis in children.…”

Antibodies against adeno-, cytomegalo- and rubella viruses in Australia-antigen-negative sera from patients with infectious hepatitis

“…Although sera from patients with acute icteric Weil's disease due to Lepto8pira spp. do not show increased titres of antibody neutralizing adenovirus (Alwen & Fulton, 1968), and increases in antibody to adenovirus may not be a general feature of diseases of the liver causing jaundice, it would be of great interest to extend the survey of antibody neutralizing adenovirus to include sera from patients with liver diseases other than infectious hepatitis, and particularly to sera from patients with Australia antigen.…”

Studies of an outbreak of acute hepatitis A: II. Antibody changes to cytomegalovirus and herpesvirus

“…Compared with the relative paucity of virus-related antibody studies in chronic hepatitis, many studies have shown an association between various respiratory and enetric viruses and outbreaks of acute hepatitis A (Davis, 1961;Liebhaber et al, 1965;Hatch and Siem, 1966;Hartwell et al, 1968;Zuckerman et al, 1968;Hatch and Swanson: 1969;Shulman and Barker, 1969;Berquist et al, 1972;Alwen, 1973). Moreover, recently Almeida reported seroconversions to several unidentified faecal antigens with virus morphology in patients with infectious hepatitis (Almeida et al, 1974).…”