Antibody to Hepatitis C Virus in German Blood Donors

“…Assays, first of the antibody (anti-HCV) and lately for the HCV antigen (HCV RNA), have been developed [4,5]. Prevalence rates among blood donors have been reportedly low in most European countries: 0.24 to 0.79% in Germany [6]; 0.87% in Italy [7]; and 0.5 to 1% in the United Kingdom [8]. One report from Spain gave a prevalence rate of 7.3% [9].…”

mentioning

confidence: 99%

Prevalence of Antibodies to Hepatitis C Virus in Blood Donors in Riyadh

et al. 1991

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“…The prevalence of anti-HCV was similar or even lower in The prevalence of anti-HCV among these two healthy groups suggested that HCV carrier rate is about 2.6-2.8%. This is higher than the values reported previously from Japan, USA and European countries ranging 0.5-1.5% (6,8,9,(12)(13)(14)(15) by the use of the same assay system described here. In Thailand, 3.1% of the population under the age of 30 were positive, whereas only 0.45% of the normal population of those ages in Japan had HCV antibody (K. Nishioka, personal communication).…”

Section: And Discussioncontrasting

confidence: 72%

Prevalence of Hepatitis C Virus Antibody Among Healthy Blood Donors and Non-A, Non-B Hepatitis Patients in Thailand

Boonmar¹,

Pojanagaroon²,

Watanabe³

et al. 1990

JJMSB

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SUMMARY:With the antigen expressed in yeast from a cDNA clone encoding a non-structural region of newly discovered hepatitic C virus (HCV) genome, the prevalence of HCV antibody in people in Thailand was investigated. Antibody was detected in 2.6% of healthy blood donors and in 2.8% of healthy pregnant women. These prevalence rates were higher than those reported previously from Japan, USA and European countries. Among community-acquired, sporadic cases of acute and chronic non-A, non-B hepatitis, however, only 5.7% and 15.4% were shown to possess the antibody, respectively. Among hepatocellular carcinoma patients who were negative for hepatitis B surface antigen in the sera, 11.1% had antibody to HCV. These seroepidemiological data suggest that HCV plays an important role as an etiological agent in Thailand; however, other agents must also be involved in etiologic agents of viral hepatitis and chronic liver disease.

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“…Estados Unidos de América (EUA), la proporción es de 0.60%, 3 en Alemania llega a 0.42%, 4 y en Hong Kong, a 0.51%. 5 En México la prevalencia de anti-VHC también varía considerablemente: en Durango es de 1.47%; 6 Méndez-Sánchez N, Baptista-González H, Sánchez-Gómez RH, Bordes-Aznar J, Uribe-Esquivel M. Prevalencia de hepatitis B y C en donadores de sangre en un hospital de tercer nivel de la ciudad de México.…”

unclassified