Anticariogenic Activity of Gnidia glauca (Fresen.) Gilg, Pothos scandens L. and Elaegnus kologa Schlecht

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“…Ji et al isolated four coumarins including 7-methoxycoumarin (5), 7-hydroxy-8-methoxycoumarin (6), 6-hydroxy-7methoxycoumarin (7), and imperatorin (8) from P. chinensis. (18) and liquiritigenin (19) were isolated from P. scandensand P. chinensis. 4,10,14…”

“…Junaid et al studied anticariogenic activity of the methanol extract of P. scandens leaf against some clinical isolates of Streptococcus mutans recovered from dental caries patients. 18 They showed the inhibition of the growth with a zone of inhibition 1.1 to 1.9 by testing for their sensitivity to the extract by Agar well diffusion method. Kim et al, evaluated the anti-inflammatory activity of ethanol extract of P. scandensin lipopolysaccharide-stimulated murine RAW 264.7 cells.…”

“…Fig.-4: Structures of Flavonoids(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30)(31) …”

Commentary on Therapeutic Potential of Gnidia glauca: A Novel Medicinal Plant

“…A significant anticariogenic activity against Streptococcus mutans by the methanolic extract of G. glauca leaves was reported recently. The active extracts showed a high total phenolic (126.25 ± 0.20 µg GAE/ mg) and flavonoid (25.75 ± 0.10 µg CE/mg) content [3]. G. glauca bark extract is reported to have superior antibacterial activity against urinary tract infection causing pathogens like Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Staphylococcus aureus and Enterococcus faecalisas compared to leaf and flower [4].…”