Antidiabetic activity of herbal green tea extract from white mangrove (Avicennia marina) leaves towards blood glucose level of diabetic wistar rats (Rattus novergicus)

Hardoko, Hardoko; Nafi’ah, Binti; Sasmito, Bambang Budi; Halim, Yuniwaty

doi:10.7455/ijfs.v8i2.553

Cited by 2 publications

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“…The phytochemical content of cactus flowers varies according to the extraction method of Ammar et al 25 Phytochemicals such as polyphenols compounds (flavonoids, tannins) have been reported to have multiple benefits for the maintenance of health and prevention of diseases. 27 Sabu and Kuttan 28 and Hardoko et al 29 previously confirmed the antidiabetic activity of green tea polyphenols.…”

Section: Resultsmentioning

confidence: 80%

Effect of Opuntia dejecta (Salm-Dyck) flowers in liver of fructose-fed rats: Biochemicals, enzymatic and histological studies

et al. 2021

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Phytochemical composition and antioxidant activity of flowers decoction at post-flowering stage (F3D) of Opuntia dejecta were determined. The obtained findings demonstrate that F3D has a marked antioxidant activity in all tested assays. Furthermore, the present study was designed to test the protective activity of F3D against induced Diabetes type 2 (DT2) in male rats. Those metabolic syndromes were induced by a high-fructose diet (HFD) (10% fructose solution) for a period of 20 weeks. F3D was administered orally (100 and 300 mg/kg body weight) daily for the last 4 weeks. Metformin (150 mg/kg body weight) was used as a standard drug and administrated orally for the last 4 weeks. The results showed a significant increase in blood glucose, triglycerides and hepatic markers (ALAT, ASAT and ALK-P) in HFD group. A significant increase in hepatic TBARS and a significant decrease in SOD, CAT and GPX were observed in fructose fed rats compared to control group. Administration of F3D showed a protective effect in biochemical and oxidative stress parameters measured in this study. Also, oral administration of F3D restored the histological architecture of rat liver in comparison with rats fed HFD. In conclusion, F3D attenuated hepatic oxidative stress in fructose-fed rats.

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Section: Resultsmentioning

confidence: 80%

Effect of Opuntia dejecta (Salm-Dyck) flowers in liver of fructose-fed rats: Biochemicals, enzymatic and histological studies

et al. 2021

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“…Its metabolites has potential as antioxidants, antimicrobials, antifungals and antibiotics (Rise et al,2012). A. marina has a high potential as a component of functional food like herbal tea (Hardoko et al, 2019).…”

Section: Introductionmentioning

confidence: 99%

Optimization of making process of api-api (Avicennia marina) mangrove leaves stew with response surface methodology analysis

Nida

Dewi

Riyadi

2022

Bioma

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The leaves of the A. marina have the potential to be developed into functional foods such as tea. It contains alkaloids, saponins, tannins, phenolics, flavonoids, triterpenoids and glycosides, with antioxidants, antimicrobials, antifungals and antibiotics potential. This study want to examine the effect of oven duration and stewing duration on the stewing quality of A. marina leaves and to determine the optimum oven duration and stewing duration using analysis of Response Surface Methodology (RSM). The lower limit of the oven time used is 2 hours and the upper limit is 6 hours, while the lower limit for stewing is 5 minutes and the upper limit is 15 minutes. Analysis of the data carried out is a test for tannin levels, antioxidant activity test and hedonic test. Data of tannins and antioxidant activity processed using Software Design Expert 11. The progam suggests formulate with oven duration is 4 hours and stewing duration is10 inutes. The result of the tannin test are prdictd to produce 2.8676% and antioxidant activity 1.282 ppm. The desirability value is 0.961. that means the resulting formula is matchs.

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Antidiabetic activity of herbal green tea extract from white mangrove (Avicennia marina) leaves towards blood glucose level of diabetic wistar rats (Rattus novergicus)

Cited by 2 publications

References 0 publications

Effect of Opuntia dejecta (Salm-Dyck) flowers in liver of fructose-fed rats: Biochemicals, enzymatic and histological studies

Effect of Opuntia dejecta (Salm-Dyck) flowers in liver of fructose-fed rats: Biochemicals, enzymatic and histological studies

Optimization of making process of api-api (Avicennia marina) mangrove leaves stew with response surface methodology analysis

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