Antidiabetic Effect and Antioxidant Potential of<i>Rosa canina</i>Fruits

BackgroundThe theoretical, but especially the practical values of identifying the biochemical compounds from the Rosa canina L. fruits are of present interest, this aspect being illustrated by the numerous researches. It was reported that the Rosa canina L. fruit, with its high ascorbic acid, phenolics and flavonoids contents, have antioxidant, antimutagenic and anticarcinogenic effects.This study was performed on order to evaluate the amount of the main phytochemicals (vitamin C, total polyphenols, and total flavonoids) content and their antioxidant activity.ResultsThe results obtained revealed that the average amounts of vitamin C within the studied genotypes were: 360.22 mg/100 g frozen pulp (var. transitoria f. ramosissima, altitude 1250 m) and 112.20 mg/100 g frozen pulp (var. assiensis, altitude 440 m), giving a good correlation between the vitamin C content of the rosehip and the altitude. The total polyphenols content varied from 575 mg/100 g frozen pulp (var. transitoria f. ramosissima) to 326 mg/100 g frozen pulp (var. lutetiana f. fallens). The total flavonoids content showed the highest value for var. assiensis variant 163.3 mg/100 g frozen pulp and the lowest value attributed to var. transitoria f. montivaga 101.3 mg/100 g frozen pulp. The antioxidant activity of eight rose hip extracts from wild Transylvania populations was investigated through DPPH method. The antioxidant activity revealed a good correlation only with vitamin C content and total polyphenols.ConclusionEight Rose hip fruit species were compared taking into consideration the ascorbic acid, total polyphenols, total flavonoids contents and their antioxidant activity. Based on these results, two of the rosehip genotypes that were analysed could be of perspective for these species’ amelioration, due to their content of phytochemicals mentioned above. These varieties are var. transitoria f. ramosissima (Bistrita-Nasaud, Agiesel) and var. transitoria f. montivaga (Bistrita-Nasaud, Salva) which can be used as a potential source of natural antioxidants.

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“…[4,5]. The nutrients and technological properties were determined in Rosa canina L. fruits (rosehips) in order to investigate potential uses [4].…”

Section: Introductionmentioning

confidence: 99%

“…[20]. Moreover, the research done by Orhan et al [5], showed that the dog rose hips also have antidiabetic properties (probably due to their monosaccharids, oligosaccharids and pectins content).…”

Section: Introductionmentioning

confidence: 99%

Bioactive compounds and antioxidant activity of Rosa canina L.biotypes from spontaneous flora of Transylvania

Roman

Stănilă

2013

Chemistry Central Journal

163

116

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“…Besides, the Ros and leaves of the plant have also been used against bronchitis. To date, reports on the antioxidant, antiinflammatory, antiulcer, antimicrobial, antimutagenic effects and inflammatory cytokines inhibitory activity of R. canina Fs are available [53].…”

Section: Rosa Canina Lmentioning

confidence: 99%

Çocuk Hastaliklarinda Geleneksel Olarak Kullanilan Bazi Bi̇tki̇ler

SARI,

KÜLTÜR,

KOÇYİĞİT

2023

Ankara Ecz. Fak. Derg.

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Objective: Different types of pediatric diseases negatively affect the lives of many people, physically. Here, we aimed to document some medicinal plants used as traditional folk medicine in pediatrics treatment. Result and Discussion: 117 taxa and 53 families have been identified as traditional herbal medicines used in defined pediatric diseases. The most frequently used medicinal plant species according to the number of citations Foeniculum vulgare Mill., Juglans regia L., Dryopteris filix-mas (L.) Schott, Rosa canina L., Mentha x piperita L., Matricaria chamomilla L. All findings are expected to form the basis for new pharmaceutical products and become a handbook for healthcare professionals.

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“…fruits Reduce blood glucose level, regulate lipid metabolism by inhibiting fat accumulation (mainly visceral), decrease serum triglycerides, regeneration of pancreas β-cells, increase expression of insulin-dependent genes Gck and Ptp1b. Ninomiya et al (2007), Orhan et al (2009), Taghizadeh et al (2016), Fattahi et al (2017, Bahrami et al (2020) Arctium spp. roots Decrease of blood glucose, increase of insulin synthesis, suppression of lipid synthesis by activating 5′-adenosine monophosphate activated protein kinase, regulated the expression of sterol regulatory elementbinding protein-1 and stearoyl-CoA desaturase.…”

Section: Mechanisms Referencesmentioning

confidence: 99%

Medical Species Used in Russia for the Management of Diabetes and Related Disorders

et al. 2021

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Background: Polyherbal mixtures called “medical species” are part of traditional and officinal medicine in Russia. This review aimed to analyze medical species used in Russia for the treatment of diabetes and related disorders. The information relevant to medical species, diabetes, and obesity was collected from local libraries, the online service E-library.ru, and Google Scholar. The prediction of the antidiabetic activity for the principal compounds identified in plants was performed using the free web resource PASS Online.Results: We collected and analyzed information about the compositions, specificities of use, and posology of 227 medical species. The medical species represent mixtures of 2–15 plants, while the most frequently mentioned in the literature are species comprising 3–6 plants. The top 10 plants among the 158 mentioned in the literature include Vaccinium myrtillus L., Phaseolus vulgaris L., Taraxacum campylodes G.E. Haglund., Urtica dioica L., Rosa spp., Hypericum spp., Galega officinalis L., Mentha × piperita L., Arctium spp, and Fragaria vesca L. The leading binary combination found in medical species comprises the leaves of V. myrtillus and pericarp of P. vulgaris; leaves of V. myrtillus and leaves of U. dioica; and leaves of V. myrtillus and aerial parts of G. officinalis. In triple combinations, in addition to the above-mentioned components, the roots of T. campylodes are often used. These combinations can be regarded as basic mixtures. Other plants are added to improve the efficacy, treat associated disorders, improve gastrointestinal function, prevent allergic reactions, etc. Meanwhile, an increase in plants in the mixture necessitates advanced techniques for quality control. A feature of medical species in Russia is the addition of fresh juices, birch sap, seaweeds, and adaptogenic plants. Modern studies of the mechanisms of action and predicted activities of the principal compounds from medicinal plants support the rationality of polyherbal mixtures. Nevertheless, the mechanisms are not well studied and reported due to the limited number of compounds. Further investigations with calculations of synergistic or additive indices are important for strengthening the scientific fundamentals for the wider use of medical species in the therapy of diabetes. Two medical species, “Arfazetin” (7 medicinal plants) and “Myrphasinum” (12 medicinal plants), are approved for use in officinal medicine. The efficacy of these species was confirmed in several in vivo experiments and clinical trials. According to modern regulatory rules, additional experiments and clinical trials are required for more detailed investigations of the mechanisms of action and confirmation of efficacy.Conclusion: We believe that the scientifically based utilization of rich plant resources and knowledge of Russian herbal medicine can significantly contribute to the local economy as well as to the sectors seeking natural healing products.

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Antidiabetic Effect and Antioxidant Potential ofRosa caninaFruits

Cited by 47 publications

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Bioactive compounds and antioxidant activity of Rosa canina L.biotypes from spontaneous flora of Transylvania

Bioactive compounds and antioxidant activity of Rosa canina L.biotypes from spontaneous flora of Transylvania

Çocuk Hastaliklarinda Geleneksel Olarak Kullanilan Bazi Bi̇tki̇ler

Medical Species Used in Russia for the Management of Diabetes and Related Disorders

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