Antiepileptic effects of short-wave radiation in hypogeomagnetic conditions

Abstract

<jats:title>Abstract</jats:title><jats:p>The work was dedicated to investigation of dynamics of epileptic activity in conditions of extremely high frequency electromagnetic waves (EHF) radiation (7,1 mm, 0,1 mW/cm2) upon focal epileptic activity. Epileptic activity was penicillin-induced (10,000 IU/ml) in the frontal region of the brain cortex in myorelaxed and artificially ventilated rats under acute experimental condition. Thermal effects were absent as far as absorbed dosage of energy did not exceed 0,1 J/ animal. It was established that preliminarily performed hypogeomagnetic period (3,0 h) with the inductivity of geomagnetic field at 5×10−8 Tesla caused the intensification of antiepileptic effects of EHF (15,0 min of exposure). It was pronounced in the form of decrease of foci intensity and significant reduction of lifespan of foci — up to 115,3±13,4 minutes, which was both significant when compared with separate effects of hypogeomagnetic influence (187,3±12,5 min) and EHF (15,0 minutes of exposure) effect (164,2±12,5 minutes) (P&lt;0,05). Besides, EHF (15,0 min) which was made after 3,0 h exposure to hypogeomagnetic influence suppressed generalized seizures in amygdalarly kindled rats.</jats:p>

Smart devices/mobile phone in patients with epilepsy? A systematic review

“…The primary search yielded 7766 studies (PubMed, n = 1227; Scopus, n = 6470; Google Scholar, n = 69). Only 33 studies met all the inclusion criteria and were included in the current systematic review 15–47 (Figure 1). Table 1 shows a summary of these studies.…”

“…In total, 19 manuscripts were based on animal/computational studies and 14 articles reported human investigations. Among the animal studies, 10 articles suggested detrimental effects by electromagnetic fields (EMFs) on brain function/seizure activity (eg, mobile phone radiofrequency can induce seizures in rats following their facilitation by sub‐convulsive doses of picrotoxin 22 ), while nine studies negated this hypothesis or even showed beneficial effects of EMFs in animals (eg, extremely high frequency electromagnetic wave radiation suppressed generalized seizures in kindled rats 33 ). Among human studies, seven studies suggested detrimental effects by EMFs on brain function/seizure activity (eg, The prolonged use (>4h per day) of smart technology devices was associated with higher reporting of seizures 45 ), while seven studies negated this hypothesis (eg, acute GSM exposure in patients slightly influenced their EEG properties, without any clinical relevance 35 ).…”