Antifeedant and antiphytopathogenic metabolites from co-culture of endophyte Irpex lacteus, phytopathogen Nigrospora oryzae, and entomopathogen Beauveria bassiana

Yin, Hai-Yue; Yang, Xue‐Qiong; Wang, Dai-Li; Zhao, Tong-De; Wang, Cuifang; Yang, Ya‐Bin; Ding, Zhong‐Tao

doi:10.1016/j.fitote.2020.104781

Cited by 11 publications

(3 citation statements)

References 23 publications

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“…One of the ways to decrease the problem is to obtain antifeedant compounds. Endophytic fungi produced many compounds studied as antifeedants [ 104 , 105 , 106 ]. Li et al studied antifungal, BSLT, and antifeedant activity in the previous study.…”

Section: Bioactivity Of Secondary Metabolites Isolated From Endophyti...mentioning

confidence: 99%

Phytochemistry and Biological Activities of Endophytic Fungi from the Meliaceae Family

2023

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Meliaceae plants are found worldwide in tropical or subtropical climates. They are important ethnobotanically as sources of traditional medicine, with 575 species and 51 genera. Previous research found that microorganisms are plant pioneers to produce secondary metabolites with diverse compound structures and bioactivities. Several plants of the Meliaceae family contain secondary metabolites isolated from endophytic fungi. Furthermore, related articles from 2002 to 2022 were collected from SciFinder, Google Scholar, and PubMed. About 276 compounds were isolated from endophytic fungi such as terpenoids, polyketides, lactones, pyrones, quinone, anthraquinones, xanthones, coumarines, isocoumarines, resorcylic acid lactones, cytochalasins, aromatics, ester, quinols, alkaloids, nitro compound, fatty acids, and sugars with bioactivities such as antioxidant, antibacterial, antifungal, anti-influenza, neuroprotective activities, anti-HIV, cytotoxic, allelopathic, anti-inflammatory, antifeedant effects, and BSLT toxicity. Meanwhile, secondary metabolites isolated from endophytic fungi were reported as one of the sources of active compounds for medicinal chemistry. This comprehensive review summarizes the ethnobotanical uses and secondary metabolites derived from Meliaceae endophytic fungi.

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Section: Bioactivity Of Secondary Metabolites Isolated From Endophyti...mentioning

confidence: 99%

Phytochemistry and Biological Activities of Endophytic Fungi from the Meliaceae Family

2023

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“…The addition of some amino acids to the liquid culture medium or cultivation of B. bassiana on brain tissues of the ant Camponotus pennsylvanicus stimulated the production of several new variants of beauveriolides [ 251 , 252 ]. In a mixed culture of B. bassiana , the endophyte Irpex lacteus , and the phytopathogen Nigrospora oryzae , five new compounds were identified, but of the 20 isolated substances, tremulendiol A at a concentration of 6.25 µg/cm 2 had the maximum toxicity for silkworm [ 253 ]. In-depth metabolomic studies using MS/MS and high-resolution mass spectrometry revealed new compounds in Metarhizium spp., in particular, previously undescribed destruxins [ 254 ].…”

Section: Promising Areas Of Researchmentioning

confidence: 99%

The Chemical Ecology Approach to Reveal Fungal Metabolites for Arthropod Pest Management

Berestetskiy

2021

Microorganisms

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Biorational insecticides (for instance, avermectins, spinosins, azadirachtin, and afidopyropen) of natural origin are increasingly being used in agriculture. The review considers the chemical ecology approach for the search for new compounds with insecticidal properties (entomotoxic, antifeedant, and hormonal) produced by fungi of various ecological groups (entomopathogens, soil saprotrophs, endophytes, phytopathogens, and mushrooms). The literature survey revealed that insecticidal metabolites of entomopathogenic fungi have not been sufficiently studied, and most of the well-characterized compounds show moderate insecticidal activity. The greatest number of substances with insecticidal properties was found to be produced by soil fungi, mainly from the genera Aspergillus and Penicillium. Metabolites with insecticidal and antifeedant properties were also found in endophytic and phytopathogenic fungi. It was noted that insect pests of stored products are mostly low sensitive to mycotoxins. Mushrooms were found to be promising producers of antifeedant compounds as well as insecticidal proteins. The expansion of the number of substances with insecticidal properties detected in prospective fungal species is possible by mining fungal genomes for secondary metabolite gene clusters and secreted proteins with their subsequent activation by various methods. The efficacy of these studies can be increased with high-throughput techniques of extraction of fungal metabolites and their analysis by various methods of chromatography and mass spectrometry.

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“…6 In the previous work, the antagonistic coculture with phytopathogen and the culture method activated the silent BGCs of endophyte to produce antiphytopathogenic and insecticidal cryptic metabolites for the natural agrochemical discovery. 7,8 The metabolites from the coculture of Pu-erh tea endophyte Daldinia eschscholtzii and phytopathogen Colletotrichum pseudomajus indicated the obvious difference by comparing with those of monocultures, and the fungal forms of coculture were more likely to that of D. eschscholtzii for the inhibition against C. pseudomajus. Moreover, in order to activate the more silent BGCs, the different culture methods were applied to the cocultures of C. pseudomajus and D. eschscholtzii.…”

Section: ■ Introductionmentioning

confidence: 99%

Antifeedant, Antifungal Cryptic Polyketides with Six Structural Frameworks from Tea Endophyte Daldinia eschscholtzii Propelled by the Antagonistic Coculture with Phytopathogen Colletotrichum pseudomajus and Different Culture Methods

Chen,

Yang,

Wang

et al. 2023

J. Agric. Food Chem.

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The antagonistic coculture with tea phytopathogen Colletotrichum pseudomajus induces antifungal cryptic metabolites from isogenesis endophyte Daldinia eschscholtzii against tea phytopathogens. Sixteen new polyketides with six structural frameworks including ten cryptic ones, named coldaldols A−C (1−3), collediol (5), and daldinrins A−L (10−20 and 23), were found from the coculture of C. pseudomajus and D. eschscholtzii by different culture methods. The unique framework of compounds 11 and 12 featured a benzopyran-C 7 polyketone hybrid, and compounds 13−16 were characterized by the novel benzopyran dimer. The structures were determined mainly by spectroscopic methods, including extensive one-dimensional (1D), two-dimensional (2D) NMR, high resolution electrospray ionisation mass spectroscopy (HRESIMS), ECD calculation, and single-crystal X-ray diffraction. The configuration of acyclic compounds 5 and 18 were determined by application of the universal NMR database. Most compounds showed significant antifungal activities against the tea pathogens C. pseudomajus and Alternaria sp. with MICs of 1−8 μg/mL. Compound 12 had stronger antifungal activity than that of positive drug nystatin. The ether bond at C-4 of the benzopyran derivative increased the antifungal activity. Compounds 4−9 and 11−23 showed antifeedant activities against silkworms with feeding deterrence indices of 15−100% at the concentration of 50 μg/cm 2 .

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Antifeedant and antiphytopathogenic metabolites from co-culture of endophyte Irpex lacteus, phytopathogen Nigrospora oryzae, and entomopathogen Beauveria bassiana

Cited by 11 publications

References 23 publications

Phytochemistry and Biological Activities of Endophytic Fungi from the Meliaceae Family

Phytochemistry and Biological Activities of Endophytic Fungi from the Meliaceae Family

The Chemical Ecology Approach to Reveal Fungal Metabolites for Arthropod Pest Management

Antifeedant, Antifungal Cryptic Polyketides with Six Structural Frameworks from Tea Endophyte Daldinia eschscholtzii Propelled by the Antagonistic Coculture with Phytopathogen Colletotrichum pseudomajus and Different Culture Methods

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